Psychedelic research notes and analysis

Psychedelic Research Recap: May 2026

May 2026 added 31 psychedelic research papers, led by patient studies in depression, suicidality, and addiction, with further work on mechanisms, safety, practice, and naturalistic use.

The Personnel-Hours Question in Psychedelic Therapy

An evidence-first guide to supervised staff-hours in psychedelic therapy, and why protocol design, role mix, and regional systems shape cost and access.

Psychedelic Research Recap: April 2026

April 2026 psychedelic research highlighted clinical trials in cancer, depression, suicidality, OCD and BPD, alongside mechanistic, methodological and review papers on psychedelics, ketamine, esketamine and MDMA.

Payer Evidence Checklist for Psychedelic Therapies

What payers and HTA bodies need before psychedelic therapies can move from promising clinical evidence to coverage decisions.

Psychedelic Therapy Access in Europe: Comparison

Compare ketamine and esketamine licensing, reimbursement, and patient access pathways across selected European markets.

Comparative access pathways: Oregon, Canada and Australia

A comparative implementation summary of access pathways in Oregon, Canada and Australia, with practical implications for equity and scale.

EU and UK HTA in 2026: Implications for reimbursement readiness

How EU HTA implementation and UK methods updates affect reimbursement strategy for psychedelic interventions.

PsyPal 2026: What the guidance changes for implementation strategy

A practical synthesis of the 2026 PsyPal guidance paper for implementation and access strategy in Europe and the UK.

Potential Reimbursement and Access Pathways

As psychedelic therapies move closer to approval in Europe, healthcare systems face a crucial question: How will patients access these treatments? The path...

Critical Observations from Collaborators

The integration of psychedelic therapies into European healthcare systems represents a complex challenge that extends beyond the scope of traditional...

Introduction to Psychedelics and Reimbursement

Psychedelic substances have been used for millennia in various indigenous cultures for religious, spiritual, and healing purposes. For instance,...

The Drug Development to Reimbursement Pathway

Bringing a new medicine to patients involves many steps, from drug creation to ensuring patient access. Each step presents unique challenges, from testing...

Clinical Development of Psychedelic Therapies

The development of psychedelic therapies is rapidly advancing, with several promising compounds progressing through Phase II and Phase III clinical trials,...

Payer and Health Technology Assessments

Securing access to psychedelic therapies requires working with payers and health technology assessment (HTA) bodies after regulatory approval. These...

Reimbursement Landscape in Europe

In Europe, while the European Medicines Agency (EMA) handles drug approvals centrally for most countries, each country makes its own decisions about...

Challenges and Barriers to Reimbursement

Getting psychedelic therapies approved and paid for by healthcare systems is challenging. While these treatments show promise for mental health conditions,...

Solutions and Recommendations

This chapter explores practical solutions for integrating psychedelic therapies into European healthcare systems. Building on the previous chapter's...

Ensuring Equitable Access

As psychedelic therapies move closer to approval and implementation across Europe, ensuring fair and equal access becomes a critical challenge. Early...

Reimbursement Pathways for Psychedelic Therapies: An Overview

Mental health disorders impose a severe and growing societal and economic burden across Europe. Both national governments and the European Union (EU) now...

Psychedelic Research Recap: March 2026

March 2026 brought a strong run of clinical trials, real-world studies, mechanistic papers, and reviews across psilocybin, ketamine, MDMA, LSD, DMT, 5-MeO-DMT and related compounds.

Top 10 Novice Psychedelic Papers

A curated Blossom Top-10 reading list covering Novice Psychedelic, with linked papers from the psychedelic research database.

Top 10 Psychedelic-Assisted Therapy Papers

A curated Blossom Top-10 reading list covering Psychedelic-Assisted Therapy, with linked papers from the psychedelic research database.

Top 10 Psychedelics in the Treatment of Depression Papers

A curated Blossom Top-10 reading list covering Psychedelics in the Treatment of Depression, with linked papers from the psychedelic research database.

Top 10 Psychedelics Papers of 2020

Psychedelics research has been on a roll in 2020. Whilst much of the outside world dealt with a global pandemic, research on psychedelics continued.

Top 12 Psychedelics and Serotonin Receptors Papers

A curated Blossom Top-12 reading list covering Psychedelics and Serotonin Receptors, with linked papers from the psychedelic research database.

Top 12 Ketamine for Mental Health Papers

A curated Blossom Top-12 reading list covering Ketamine for Mental Health, with linked papers from the psychedelic research database.

Top 10 Articles on Psychedelics and Integration

A curated Blossom Top-10 reading list covering Articles on Psychedelics and Integration, with linked papers from the psychedelic research database.

Top 10 Articles on Psychedelics and Music

A curated Blossom Top-10 reading list covering Articles on Psychedelics and Music, with linked papers from the psychedelic research database.

Top 10 Psychedelics and SSRIs

A curated Blossom Top-10 reading list covering Psychedelics and SSRIs, with linked papers from the psychedelic research database.

Top 10 Cited Psychedelic Papers

A curated Blossom Top-10 reading list covering Cited Psychedelic, with linked papers from the psychedelic research database.

Psychedelic Research Recap: February 2026

A monthly recap of psychedelic research papers published in February 2026, covering clinical studies, microdosing, belief, brain imaging, reviews, and trial context.

Psychedelic Research Recap: January 2026

January 2026 brought several clinical reports, a healthy volunteer study on time perception, and broader reviews on how psychedelic therapies may fit into care systems.

Psychedelic Research Recap December 2025

In December 2025, psychedelic studies ranged from tightly controlled placebo designs to open-label clinic pilots and real-world chart reviews, with several

Psychedelic Research Recap November 2025

Psychedelic research in November examined microdosing outcomes, brain criticality and plasticity mechanisms, and clinical applications for depression, PTSD, and

Psychedelic Research Recap October 2025

Psychedelic research in October investigated brain plasticity, set and setting, and microdosing.

Psychedelic Research Recap September 2025

Psychedelic Research Recap August 2025

Psychedelic research in August 2025 (162 studies, 10 added to the database) looked at psilocybin for PTSD, economic evaluations, and much more.

Psychedelic Research Recap July 2025

Psychedelic research in July 2025 (181 studies, 18 in database) looked at the receptors psychedelics influence, naturalistic psychedelic use.

Psychedelic Research Recap June 2025

Psychedelic research in June 2025 (146 studies, 18 added to the database) looked at long-term effects of psilocybin therapy for depression, 'meaning of life'

Psychedelic Research Recap May 2025

Psychedelic research in May 2025 shows ketamine saves healthcare costs, esketamine remains safe long-term, and these therapies work differently than expected.

Psychedelic Research Recap April 2025

In April 2025, psychedelic researchers published 172 studies and we've added 17 new papers to the database. This month featured ketamine for smoking cessation

Psychedelic Research Recap March 2025

In March 2025, 138 psychedelic studies were published we've added 11 new papers to the database.

Psychedelic Research Recap February 2025

February 2025's psychedelic research explores therapeutic applications, mechanisms of action, brain effects, and emotional experiences with 11 new studies.

Psychedelic Research Recap January 2025

In January 2025, psychedelic research saw modest activity, contributing 11 new studies and 183 linked studies.

Psychedelic Research Recap December 2024

In December 2024, psychedelic research slowed, adding 14 studies, 130 links, and insights on clinical trials, re-analyses, and global progress.

Psychedelic Research Recap November 2024

In the November recap, we explore the neuroplasticity mechanisms of psychedelics, their therapeutic applications for mental health conditions.

Psychedelic Research Recap October 2024

In October we investigate discontinuation (or the lack of this) and psychedelic treatments, 2C-B effects, and neurofeedback and psychedelics.

Psychedelic Research Recap September 2024

Psychedelic research in September 2024 covered mescaline dosing, meditation, psilocybin for veterans, harmine dosing, and more

Psychedelic Research Recap July & August 2024

The psychedelic research from July and August 2024. Covering LSD follow-up, R vs S-MDMA, and false insights after psychedelics.

Psychedelic Research Recap June 2024

Psychedelic research in June 2024 investigated the coupling of psychedelics (and benzos), the role of purging, and ethical guidelines

Psychedelic Research Recap May 2024

Psychedelic research in May 2024 investigates awe in ketamine therapy, role of therapy in PAT, touch guidelines, and more

Psychedelic Research Recap April 2024

Psychedelic research in April 2024 covers mechanisms, challenges, MDMA effects, 5-MeO-DMT, and therapies for seizures, personality disorders, & headaches.

Psychedelic Research Recap March 2024

The latest psychedelic research from March 2024 with a look at meditation, SSRIs, and safety of psychedelics, and 17 more studies.

Psychedelic Research Recap February 2024

The latest psychedelic research from February 2024 with a look at sexuality, Switzerland's unique model, and 20 more studies.

Psychedelic Research Recap January 2024

January saw new psychedelic trials on ibogaine for TBI, DMT, & psilocybin for CCHs, alongside re-analyses on psychedelic brains, and more

Psychedelic Research Links 2024

This link page serves as a centralized overview of psychedelic research studies published in 2024 that are not featured with ind. pages.

The Long Road to Access – Psychedelics as Medicines

It's a long & bumpy road ahead before we see psychedelics as medicines generally accepted. Here is my take on the pyramid by Tadeausz Hawrot.

Psychedelic Research Recap December 2023

December's psychedelic research (2023) looked at group therapy, personality, costs and microdosing LSD. 22 papers added.

Blossom Pro: Research Briefing #2 – More Group Therapy, No Therapy? and Personality Changes

Exploring psychedelic therapy: Beyond drugs, integrating psychotherapy and context for personality changes and mental health benefits.

Blossom Pro: Research Briefing #1 – 5-MeO-DMT, Group psychedelic therapy, and personality changes

Explore the latest in psychedelic research: cost-effective group therapy models, unique effects of 5-MeO-DMT, & personality changes.

The Ethical Compass of Minding to Psychotherapy: How Much Support is Necessary?

A battle of Compass Pathways (Guy Goodwin) vs the MIND Foundation (Max Wolff). The need for psychotherapy or just psychological support.

Psychedelic Research Links December 2023

This is all the other psychedelic research that came out in December 2023. These papers don't (yet) have their own page in our database.

Are Psychedelic Treatments a Bargain or a Burden? Examining the Cost-Effectiveness

As psychedelic treatments move towards FDA approval, what will access and affordability look like? We break down the cost-effectiveness data.

Psychedelic Research Recap November 2023

November's psychedelic research (2023) saw advances in ayahuasca formulations and intriguing survey findings on naturalistic use.

Psychedelic Research Links November 2023

This is all the other psychedelic research that came out in November 2023. These papers don't (yet) have their own page in our database.

Innovating Mental Health in the EU Pharma Legislation: Regulatory Pathways for Psychedelic Therapies

A summary of the EU Parliament meeting on psychedelic therapies held on November 6th 2023 co-organised by PsychedelicsEUROPE.

Psychedelic Research Recap October 2023

The latest psychedelic research from October 2023, extended DMT, survey data on extended difficulties, and new trial results.

From Dreams to Psychedelics: Tommaso’s Academic Odyssey

Tommaso Barba, a visionary in psychedelic research, advances knowledge and accessibility, bridging diverse fields for a brighter future.

Changing Psychedelic Policy for 450 Million People

PsychedelicsEUROPE is shaping the European psychedelic landscape, influencing policies, and addressing mental health crises.

Psychedelic Research Links October 2023

This is all the other psychedelic research that came out in October 2023. These papers don't (yet) have their own page in our database.

Blossom Update – October 2023

It's been quite a few months since the last update (May). In that time, Blossom has continued to expand, with us now having full summaries.

Psychedelic Research Recap September 2023

The psychedelic research that was published in September 2023. From new trials to guidelines. Psychedelic studies that were impactful.

Psychedelic Research Links September 2023

This is all the other psychedelic research that came out in September 2023. These papers don't (yet) have their own page in our database.

Psychedelic Research Recap July & August 2023

Even as many of us took time off for summer vacations, researchers in the field of psychedelics persisted in their efforts. They delved deeper into

Psychedelic Research Links August 2023

This is all the other psychedelic research that came out in August 2023. These papers don't (yet) have their own page in our database.

Psychedelic Research Links July 2023

This is all the other psychedelic research that came out in July 2023. These papers don't (yet) have their own page in our database.

Psychedelic Research Recap June 2023

June was jam-packed with psychedelic research, with (again) adding nearly one paper a day to the research database of Blossom.

Psychedelic Research Links June 2023

This is all the other psychedelic research that came in June 2023. These papers don't (yet) have their own page in our database.

Psychedelic Science 2023 – Blossom – A History & Outlook

Psychedelic Science 2023 slides from Blossom's Floris Wolswijk on the history & outlook of psychedelic science

Psychedelic Research Recap May 2023

MDMA & LSD, masking ketamine with anaesthesia, and no blinding. This and more in the May 2023 psychedelic research recap.

Blossom Update – May 2023

Over the past month, I've done more interviews with (potential) customers and some for Lucid News. For both, the results will materialise over the coming months

Psychedelic Research Links May 2023

The research papers on psychedelics that came out in May 2023. Links to chemistry, reviews, case studies on psychedelics.

Psychedelic Research Recap April 2023

April was a month marked by nearly a dozen brain imaging studies on the effects of psychedelics. Jumping out is the highly anticipated extended DMT study.

Breaking Convention puts the psychedelic back into psychedelic conferences

Journey to the druidic lands of Exeter for a gathering of science and spirituality. Join me in revisiting Breaking Convention 2023.

Psychedelic Research Links April 2023

The research papers on psychedelics that came out in April 2023. Links to chemistry, reviews, case studies on psychedelics.

Blossom Update – April 2023

Since the February update, I've continued working on expanding the resources that are available on Blossom.

Psychedelic Research Recap March 2023

March psychedelic research investigated LSD microdosing, brain mechanisms, borderline personality disorder. All captured in our recap.

Psychedelic Research Links March 2023

This is all the other psychedelic research that came in March 2023. These papers don't (yet) have their own page in our database.

Psychedelic Research Recap February 2023

February presented another productive month for psychedelic research. This recap covers intracellular neuroplasticity, EU regulation, and more

Exploring the Challenges of Psychedelic Integration

Psychedelic experiences can be challenging to integrate into life. They can bring about feelings of anxiety, confusion, & existential crisis. 

Psychedelic Research Links February 2023

This is all the other psychedelic research that came in February 2023. These papers don't (yet) have their own page in our database.

Blossom Update – February 2023

During January, I went back to work slowly but surely. It took a bit of time to get back up and running, but I completed the main project: finishing the first v

Psychedelic Research Recap January 2023

This January, outcomes of psychedelic use were closely examined. Studies looked at how experiences are integrated, how challenging experiences lead to growth.

Psychedelic Research Recap December 2022

In December we saw medium dose of psilocybin for depression, paradoxical wakefulness on 5-MeO-DMT, many ketamine studies

Psychedelic Research Links January 2023

This is all the other psychedelic research that came out in January 2023. These papers don't (yet) have their own page in our database.

Blossom Update – January 2023

January will see the relaunch of our psychedelics courses site and continued updates on the coverage of psychedelic science.

Is the High Cost of Psychedelic Therapy Worth It?

What are the costs of psychedelic therapy? Who will pay for them and will it even be worth it for people, insurers, and companies?

Psychedelics in the European Parliament

PAREA organised a meeting in the European Parliament on psychedelic-assisted therapies for the treatment of mental health issues.

Psychedelic Research Links December 2022

This is all the other psychedelic research that came out in December 2022. These papers don't (yet) have their own page in our database.

Blossom Update – December 2022

December will see the release of Blossom's new courses website, visualisation, and more info on research papers.

Psychedelic Research Recap November 2022

In November, psilocybin can treat TRD, antidepressants weaken the effects of psilocybin and ketanserin can stop an LSD trip.

The Severe Lack of Long-Term Psychedelic Studies

212 people that have gone through psychedelic trials for which we have data that extends beyond 3 months. We need more long-term data.

EAGx Rotterdam Fireside Chat – Psychedelics as Medicines

How can psychedelics become medicines through the effective altruism lens. A transcript of a conversation at EAGx Rotterdam.

Psychedelic Research Links November 2022

This is all the other psychedelic research that came out in November 2022. These papers don't (yet) have their own page in our database.

Blossom Update – November 2022

November will be another month of continued building for Blossom. Dynamic visualisations, paper summaries, courses incoming.

Psychedelic Research Recap October 2022

In October, natural language processing predicted clinical outcomes, esketamine is assessed in the real world & tolerance in microdosing.

Psychedelics through the lens of Effective Altruism

How psychedelics can be effective solutions to the worlds biggest problems. The effective altruism framework applied to psychedelics.

The expanding scope of psychedelics as medicines

Everyone knows about MDMA for PTSD, but what if I told you there are 21 more areas psychedelics are being researched for?

Psychedelic Research Links October 2022

The latest psychedelic research that has come out in October 2022 | The links to new research that has not been added to our main database

Psychedelic Research Recap September 2022

Research from September shows the effectivness of ketamine in the real world, how LSD can treat anxiety & how psychedelics work in the brain.

Blossom Update – October 2022

Back from ICPR, this is the update blog of Blossom for October 2022. New visualisations, extra data in the database & request for feedback.

Lessons from the Interdisciplinary Conference on Psychedelic Research 2022

The take home messages from the Interdisciplinary Conference on Psychedelic Research 2022. Novel results, DMT, and a personal note.

A short history of psychedelics as an antidepressant

Where do psychedelics become antidepressants? Lydia Nichols examines the history of psychedelic research, the current state of research, and promises for the fu

Psychedelic Research Links September 2022

The latest psychedelic research that has come out in September 2022 | The links to new research that has not been added to our main database

Psychedelic Research Recap July & August 2022

Psychedelic research in July and August 2022 moved forward with the largest psychedelic trail on addiction taking place.

Psychedelic Research Links August 2022

The latest psychedelic research that has come out in August 2022 | The links to new research that has not been added to our main database

At-home ketamine is safe and effective?

Is at-home ketamine safe to use? Researchers associated with Mindbloom - a provider of this - say yes in a study with 1250 participants

Who is going to benefit from psychedelic therapy?

Psychedelic therapy is going mainstream - it won’t be long before these therapies are rolled out in clinics across the globe

It’s time to build psychedelic infrastructure

Health systems are unprepared to offer and meet the demand for psychedelic-assisted therapy - we can start to prepare now.

Is funding for psychedelic research changing?

The legal issues and stigma surrounding psychedelics have deterred many traditional sources from funding - now, things are changing.

The next generation of psychedelics

The next generation of psychedelics is already here – let's take a look at the advantages and disadvantages.

The Size of the Psychedelic Market

Despite psychedelics remaining highly controlled – it hasn’t deterred investors and a sizeable market has developed.

Psychedelic Research Recap June 2022

Psychedelic Research in June 2022 continued at pace with re-analysis of earlier data, surveys, and some clinical trials.

Psychedelic Research Links July 2022

The latest psychedelic research that has come out in July 2022 | The links to new research that has not been added to our main database

The psychedelic patent debate rages on

Anyone following the rise of psychedelic science in recent years should be all too familiar with the efforts to patent various aspects of the psychedelic experi

Take a Look at the World’s First Atlas of Psychedelic Research

Psychedelic research is going from strength to strength. With roughly 50 psychedelic research papers published every month and the abundance of start-ups lookin

What are the costs of synthesising Schedule I drugs?

Despite the resurgence in psychedelic research in recent years – psychedelics are notoriously difficult and expensive to work with. Why is this the case and how

What does Virtual Reality offer the psychedelic experience?

Many believe that virtual reality (VR) can be used to reach a higher level of consciousness – with or without the help of psychedelics.

Psychedelic Research Recap May 2022

May was another busy month for psychedelic research as we gained further insight into how psychedelics work in the brain and more.

Psychedelic Research Links June 2022

The latest psychedelic research that has come out in June 2022 | The links to new research that has not been added to our main database

Can LSD Treat Anxiety?

Psychedelics for anxiety have been significantly understudied. Change is on the horizon with new studies by MindMed, Cybin, & more

Blossom Update – June 2022

Another research project done at Blossom | Big ICPR Science Meets Business announcement | More daily blogs about psychedelic research

Meet the psychedelic investor open about his experiences

Bek Muslimov is a Co-Founding Partner at Leafy Tunnel. He’s been investing in European life sciences and technology companies.

Meet the man making natural psychedelics in bioreactors

Meet Itay Hecht, founder of PsyRx, who aims to make psychedelics botanically at scale. Not synthetic, but natural GMP grade psychedelics.

The Opioid Crisis – can psychedelics play a role?

Opioid prescriptions for pain can be a godsend. But instead of alleviating pain, opioid addiction is killing hundreds of thousands. Can psychedelics like ibogai

Could the United Kingdom become the psychedelic research hub?

Now that the UK is out of Europe, could it become a hub for psychedelic research? Let's take a look.

How can we make psychedelics accessible and do it quickly?

BrainFutures recently a report on how to make psychedelics accessible and affordable. Here are some of the insights.

Your personality is constantly changing – can psychedelics have a positive impact?

Can psychedelics change your personality for the better? Let's take a look

Have we been thinking about pain all wrong?

Can we use psychedelics to alleviate extreme suffering?

Why and how can we preserve traditional psychedelic knowledge?

Jesse Hudson is Chief Legal Officer at Woven Science and is spearheading their El Puente initiative to give back to these communities and preserve their cultura

How to make psychedelics at scale. Insights from Peter van der Heyden – CSO at Psygen.

Peter is the CSO and co-founder of Psygen - where they make psychedelic APIs - active pharmaceutical ingredients - for research and at scale

Highlights from the PSYCH Symposium 2022

The PSYCH Symposium was another great insight into how psychedelic medicine is progressing, with lots of exciting presentations & discussions.

Meet the man making synthetic psychedelics – for research & beyond

Psychedelics - for research - need to be made somewhere. Peter van der Heyden - CSO of Psygen - told me about the process.

A quick look at the next-gen in – psychedelic – brain imaging

Looking inside the brain may help us understand how and why psychedelics work.

Blossom Update – May 2022

The additions of daily blogs to Blossom, update of work done in May on report and mapping project. Company news from Blossom.

Three reasons there aren’t more psychedelic studies on anxiety

Since the turn of the century, there have only been eight psychedelic clinical trials investigating anxiety. Of these studies, most have looked at end-of-life a

Meet the neuroscientist & army officer helping veterans get the treatment they need at Heroic Hearts

Meet Grace Blest-Hopley, the research director at Heroic Hearts. She is working towards getting veterans the (psychedelic) treatment they need

Meet the neuroscientist & army officer helping veterans get the treatment they need at Heroic Hearts

Veterans face unique mental health challenges due to their service - rates of depression, anxiety and PTSD are much higher among this group when compared to the

Can psychedelics help people with anorexia? This is what research tells us now

Three months after a high dose of psilocybin, 40% of participants with anorexia saw improvements.

An ambitious $88k crowdfunded study just launched – participate!

The research group UNITy - Understanding Neuroplasticity Induced by Tryptamines - wants to change that. The crowdfunded study - using DMT - will be the most ext

Psychedelic Research Recap April 2022

Over April, we continued to learn more about psychedelic medicine. Researchers argued that psilocybin increases global integration.

Psychedelic research from April 2022 – in 3 minutes or less

Over April, we continued to learn more about psychedelic medicine. Let's take a quick look at some of the exciting articles released into the wild in April.

Can psychedelic medicine address some of the unique challenges faced by women?

The time is ripe to develop female-focused psychedelic medicine.

Psychedelic Research Links May 2022

The latest psychedelic research that has come out in May 2022 | The links to new research that has not been added to our main database

An interesting, timely – and rejected – criticism of psychedelic research.

The key points of a recent paper critiquing a recent analyis of fMRI data from two clinical trials.

Five upcoming psychedelic clinical trials you don’t want to miss

Here are five upcoming clinical trials we're excited about.

How you can enhance the psychedelic experience – without taking more

There are ways to intensify a psychedelic experience without taking more of a substance. Here are three possible ways.

What are the most interesting ongoing clinical trials with psychedelics?

Here are five ongoing clinical trials that have got our attention.

Meet the psychiatrist investigating MDMA-assisted therapy for depression

Tor-Morten shares vital information about the upcoming MDMA-AT trial for major depression. May this psychedelic also work for depression?

Meet the psychiatrist initiating the world’s first MDMA-assisted therapy trial for depression

We caught up with Tor-Morten Kvam who is working on the world's first trial using MDMA-assisted therapy for depression.

The long & short of psychedelic-assisted therapy. Part 2 – Maximalists.

What psychedelic therapy will look like is currently a hot debate. Here we provide four points on the maximalists side of the argument.

The long & short of psychedelic-assisted therapy. Maximalists vs minimalists.

What psychedelic therapy will look like is currently a hot debate. Here we provide four points on the minimalist side of the argument.

Learn what psychoneuroimmunology is from Attila Szabo

Attila Szabo shares the most interesting insights on psychoneuroimmunology & what led him to become a psychedelic researcher

What’s the Best Psychedelic Therapy Protocol? It’s Debatable.

What will psychedelic-assisted therapy look like when it becomes available? Explore this ongoing debate within the psychedelics field.

Learn what psychoneuroimmunology is from Attila Szabo

Learn what psychoneuroimmunology is from Attila Szabo and how some psychedelics can be used to influence the immune system.

Happy Easter. Here is what we know about Christianity and psychedelics.

Psychedelics and Christianity are not two things that usually fit through the same door, here are some of the ways the two are intertwined.

Happy Bicycle Day. This is how it came to be on the 19th – and not the 16th – of April.

When Albert Hofmann was 37 years old, he experienced the world's first LSD trip on the 19th of April 1943 in Basel, Switzerland.

Psychedelic science is smaller than you think. Here are fewer than 2100 reasons it’s so.

Psychedelic science is getting a lot of positive press, but we just don't have the data to back it up just yet.

Can psychedelics heal traumatic brain injury? Early evidence suggests 3 possible routes

Traumatic brain injury currently has no good treatment options. Here are 3 possible ways psychedelics might help.

Why synthetic psychedelics are sustainable. Spare the environment, but lose the spirit?

The boom in attention surrounding psychedelics has led to unsustainable consumption patterns. There is a way out, synthetic psychedelics.

Access to psychedelics legally is very restricted. Here are 3 ways how to access them in Europe

Psychedelics are not widely available, though there are three ways to access them in Europe.

4 Ways the Psychedelic Industry is Changing: Lessons from Plant Medicine Week 2022

If you want to be successful in the transitioning psychedelic industry, you will need to know which way the wind is blowing.

Blossom Update – April 2022

Here is where we stand with Blossom in April 2022. The updates from March and the plans to keep expanding in April.

Psychedelic Research Recap March 2022

March was another busy month in psychedelic medicine with nearly 100 publications of trials, surveys, reviews, etc.

Psychedelic Research Links April 2022

This is all the other psychedelic research that came out in April 2022.

Research Briefing: Psychedelics, potential tools to unearth the mysteries of consciousness

In the Research Briefing 1) a closer look at psychedelics as a tool to explore the depths of consciousness, 2) using psychedelics to explore creativity, a look

Research Briefing: LSD back in vogue

Several studies look at LSD with renewed interested, comparing it to psilocybin, and looking at the effects in healthy participants

Blossom Update – March 2022

Update on the progress of Blossom - psychedelic insights - of March 2022 | Depression report finished & updates to database

Psychedelic Research Links March 2022

This is all the other psychedelic research that came out in March 2022.

Psychedelic Research Recap February 2022

February was another productive month for psychedelic research. LSD vs psilocybin, and a 12-month follow-up.

Do Psychedelics Boost Creativity?

A new study examines how psychedelics can help with creativity. Though the influence of psychedelics on creativity is difficult to measure ...

A Paradigm Shift in Mental Healthcare

Psychedelics are poised to be a paradigm shift in mental healthcare but what is the paradigm they are set to replace?

Research Briefing: Flashbacks after psychedelics

Flashbacks are common in psychedelic research but participants don't seem to mind. LSD influences creativity, breaking down thought patterns

Psychedelic Research Links February 2022

This is all the other psychedelic research that came out in Februrary 2022.

Psychedelic Research Recap January 2022

January brought with it the largest published clinical trial with psilocybin to date | Ketamine effective for alcoholism not PTSD for veterans

Blossom Update – February 2022

Update on the progress of Blossom - psychedelic insights - of February 2022 | New looks, reports coming together & more

MAPS Publishes Open Science Approach to Synthesizing MDMA

How do you synthesize MDMA for research & therapy? We spoke to Berra Yazar-Klosinski to learn about how MAPS PBC is making cGMP MDMA at scale

Psychedelics: A Solution to a Global Mental Health Crisis? Not likely.

Psychedelics are posied to be a paradigm shift in mental healthcare but will this paradigm shift extend beyond high-income countries?

Drug Policy: The Barriers Faced by Psychedelics and Thoughts on Overcoming Them

A change in policy surrounding psychedelics is needed. Here we discuss the barriers to change and how they might be overcome.

Research Briefing: Ketamine effective for alcoholism, not PTSD?

New research into ketamine as a medicine shows the real-world effectiveness for depression, and potential for alcoholism, data for PTSD looks worse

Psychedelics and Technology

Technological development is changing how we think about and interact with drugs while maximising the therapeutic potential of psychedelics.

Research Briefing: Wins for MDMA and psilocybin

Largest peer-reviewed study with psilocybin so far, MDMA synthesis is made accessible, NO2 could be the next antidepressant and much more.

Psychedelics Research Links January 2022

Links to all other psychedelic research from January 2022 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics Research Recap December 2021

December psychedelic research 2021 | Microdosing studies | Synthesizing MDMA & structure of psilocybin examined | NO2 review

Research Briefing: No Blue Mondays after clinical MDMA use?

New double-blind study doesn't find benefits of microdosing | The negative post-acute effects of MDMA appear to be absent in the clinical setting

Psychedelics and VR – Interview with David Glowacki

How can we combine virtual reality and psychedelics? Where can VR be applied to scientific simulation and visualization

Taking Microdosing with a Pinch of Salt

Microdosing is becoming more popular | Is there scientific merit to it | And does a new paper prove the benefits of microdosing?

Woven Science: Indigenous Communities

How can we marry psychedelic capitalism & reciprocity? | Blossom speaks to Woven Science on their approach to indigenous communities

Psychedelics Research Recap November 2021

November psychedelic research 2021 | Psychedelics alter beliefs, reduce opioid use, & the effects of microdosing | Phase I trial clear 5-MeO-DMT

Research Briefing: Improving psychedelic trials

Methodological challenges in psychedelic clinical trials | Mystical experiences in recreational use & wellbeing improvements

Psychedelics Research Links December 2021

Links to all other psychedelic research from December 2021 | The papers that didn't make it into the psychedelic research database (yet)

Research Briefing: Microdosing & neural flexibility

Those who microdose report lower anxiety & depression| Psilocybin therapy increases cognitive and neural flexibility | How can psilocybin help decrease craving

Adverse Events and Psychedelics

Psychedelics are generally safe but adverse events can occur. Understanding these events is important for psychedelics to become accessible.

Research Briefing: Patenting psychedelics

To patent or not to patent psychedelics | Getting psychedelics to a community clinic near you | The influence of cannabis on psychedelic experiences

Key Psilocybin & Depression Studies

Explore the studies that have used psilocybin (in combination with therapy) to improve (treatment-resistant) depression

Psychedelics Research Recap October 2021

October brought 26 research articles on psychedelics as medicine. Several studies explored the effects of low doses of LSD ...

Psychedelics Research Links November 2021

Links to all other psychedelic research from November 2021 | The papers that didn't make it into the psychedelic research database (yet)

Research Briefing: The potential of 5-MeO-DMT

5-MeO-DMT has the potential to become the psychedelic of choice, but we need to learn much more, human studies are limited at this time

The secrets of kratom – Interview with Jay McLaughlin

Discover the secrets of kratom, how they work, where the promise of kratom lies & how Jay McLaughlin is studying this, Salvinorin A, and more

The Psychedelics as Medicine Report – The Size of the Psychedelic Market

Expected to be north of $1 billion in revenue in the coming years | An investigation of the companies implementing psychedelic medicine

Research Briefing: EEG study provides good news for microdosing LSD

Good news for microdosing from a neuroimaging study | MDMA-assisted therapy could help those with social anxiety disorder

Broad Support for Psychedelics as Medicine from ACX Reader Survey

Nearly everyone (96%) was familiar with the use of psychedelics for the treatment of mental health conditions

Psychedelics Research Recap September 2021

September featured 30 new and exciting papers on psychedelics | Safety of psychedelics | Well-being after the ceremonial or therapeutic use

Psychedelics Research Links October 2021

Links to all other psychedelic research from October 2021 | The papers that didn't make it into the psychedelic research database (yet)

Research Briefing: Psychedelics for neurodegenerative disorders

How ayahuasca ceremony leaders regard preparation & integration | Psychedelics for treating neurodegenerative disorders such as Alzheimer's | The relative safet

Psychedelics Research Recap July & August 2021

Psychedelic research continued at pace during the summer of 2021 | Risks of psychedelics | Benefits when treating addictions

Psychedelics as Medicine Report – The Trip Report Interview Preview

Blossom sits down with Zach Heigney, founder of The Trip Report | We discuss the impact of technology on psychedelics

Psychedelics as Medicines Report – Henrik Jungaberle Interview Preview

Blossom sits down with Henrik Jungaberle, founder of the MIND Foundation & OVID Clinic | How do we implement psychedelics?

Psychedelics Research Links September 2021

Links to all other psychedelic research from September 2021 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics as Medicines Report – Consumer Attitudes Preview

Consumer attitudes towards psychedelics are turning around with 2/3 consumers supporting legalisation of psychedelics for medicinal use

Research Briefing: Psychedelics for the treatment of addictions

The considerable risks of ibogaine | Psychiatrists favourable about psychedelics as medicines | Quitting tobacco addiction after psychedelic use

Psychedelics Research Links August 2021

Links to all other psychedelic research from August 2021 | The papers that didn't make it into the psychedelic research database (yet)

Research Briefing: Making psychedelics at scale

LSD increases empathy via oxytocin independent of serotonin receptor activity | Low dose LSD engenders therapeutic processes

Psychedelics News July 2021

Psychedelic news of July 2021 highlights benefits of psilocybin mushrooms, psychedelics for PTSD, and legalization.

Research Briefing: Will psychedelics change your worldview?

Psychedelic research finds well-being changed up to two years later | Anorexia possibly helped with psychedelics

Clinical Trials

Psychedelics are set to be approved as medicines after they go through clinical trials | Learn which drugs & companies are taking the lead

Psychedelics Research Links July 2021

Links to all other psychedelic research from July 2021 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics Research Recap June 2021

Psychedelic research in June 2021 | From those who use mental health services to the general public | fMRI studies new findings

Research Briefing: What do patients think of psychedelics as medicines?

Are patients ready for psychedelics as medicines? A survey study provides answers | Microdosing still not in the clear

Research Briefing: Predicting who will quit drugs based on their trip report

Find out how machine learning is being used to find out who quits drugs after a psychedelic trip | The small base on which fMRI studies stand

Research Briefing: Breaking free from a negativity bias with psychedelics

Psychedelics help on break free from negative bias thought loops | Positive long-term outcomes after bad trips

Psychedelics Research Links June 2021

Links to all other psychedelic research from June 2021 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics Research Recap May 2021

Psychedelic research in May 2021 | MAPS MDMA study data | psychedelics and genes | Many psychedelic centre studies

Research Briefing: Your genes and psychedelics

The intensity of an LSD experience as predicted by your genes | A brain on psilocybin becomes less segregated

Research Briefing: The most complete picture of our brain on psychedelics

The most complete picture we have of our brains on LSD | Psychedelics may help us explore consciousness, but be wary

Research Briefing: MDMA versus PTSD and Psychedelics versus COVID

MAPS reports a successful trial of MDMA-assisted therapy for PTSD | Psychedelic users appear to be more resilient in the face of Covid

Long term experience with psychedelics and empathogens

Claude Weill argues that the successful integration of psychedelics and empathogenic substances can lead to long-term meaning and fulfilment.

Research Briefing: In awe of molecular tools

A new biosensor helps identify which molecules are hallucinogenic | Microdosing and awe, experiencing the sublime on psilocybin

Psychedelics Research Recap April 2021

Psychedelic research in April 2021 | Psychedelics against SSRIs | Mice take a break from tripping | New psychedelics discovered

Psychedelics Research Links May 2021

Links to all other psychedelic research from May 2021 | The papers that didn't make it into the psychedelic research database (yet)

Research Briefing: Hallucinogenic effects not necessary?

Psilocybin pitted against antidepressant and wins on many accounts | What if the anti-depressant & hallucinogenic effects of psychedelics are independent?

The Depth of Neurons

An experiment, done with neuronal cells from ferrets, says it shows that neurons store numbers. Can psychedelics change the storage of info?

Research Briefing: Psychedelic Creativity?

Creativity is impaired whilst under the influence of psilocybin | Ethical and legal considerations for clinicians

Psychedelics Research Links April 2021

Links to all other psychedelic research from April 2021 | The papers that didn't make it into the psychedelic research database (yet)

Research Briefing: The positives of ketamine and negatives of ayahuasca

Ketamine has positive benefits up to 6 weeks later | How ayahuasca ceremonies can lead to negative experiences

Research Briefing: Psychedelics work in (less) mysterious ways

Positive interpersonal experience during a retreat | What predicts your response to MDMA | LSD and your autonomic nervous system

Research Briefing: Blowing your mind, according to science

Shamanic practitioners show similar brain changes as those on a high dose of psychedelics | Psychedelics and mindfulness meditation

Research Briefing: Overestimating outcomes of psychedelic RCTs

Breaking blinds in randomized controlled trials is leading to overestimation of the outcomes | The positive outcomes of an ayahuasca retreat

Psychedelics Research Links March 2021

Links to all other psychedelic research from March 2021 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics News March 2021

March was a great month for psychedelic research. The psychedelic news this month: patents, microdosing study, placebo effects, funding for therapists

Psychedelics Research Recap March 2021

March 2021 psychedelic research started with the largest microdosing study with psilocybin, LSD, and other psychedelics.

Psychedelic Apps

Apps made to help with a psychedelic experience | From preparation and information to apps to use during a psychedelic trip

Psychedelics Research Links February 2021

Links to all other psychedelic research from February 2021 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics News February 2021

February 2021 was another great month for psychedelic news, research and advocacy. Psychedelics are becoming more mainstream.

Psychedelics Research Recap February 2021

February 2021 was another great month for psychedelic research. The BIMA study used MDMA-assisted psychotherapy for alcoholism (AUD)

Psychedelics Research Links January 2021

Links to all other psychedelic research from January 2021 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics News January 2021

This is the Psychedelics News in January 2021. Studies with psychedelics are continuing into this new year.

Psychedelics Research Recap January 2021

Psychedelic research in January 2021 | A meta-analytic review found psychedelics to improve the mood of patients with depression

Psychedelics Research Links December 2020

Links to all other psychedelic research from December 2020 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics News December 2020

December was no sleepy winter month this year as the psychedelics field keeps pushing forward. We identified seven new significant papers that advanced the fiel

Psychedelics Research Recap December 2020

This December 2020, psychedelic research looked into many different aspects of the psychedelic experience | Nature-relatedness

Psychedelics Research Links November 2020

Links to all other psychedelic research from November 2020 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelic Communities

Psychedelic communities communities offer a place to get together and discuss the science, culture, and use of psychedelics

Psychedelics Research Recap November 2020

This November 2020 proved to be another fruitful month for psychedelic research | Psychedelics for more mental illnesses

Psychedelics News November 2020

In November 2020, psychedelics had a big win in decriminalization, studies expanded the scope where psychedelics can help, and companies raked in the listings a

Psychedelics Research Links October 2020

Links to all other psychedelic research from October 2020 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics Research Recap October 2020

October was possibly the most active month this year for psychedelic research | These are building blocks that further the psychedelic field

Psychedelics News October 2020

This is the ongoing blog for psychedelics news in October 2020.

Psychedelics Research Links September 2020

Links to all other psychedelic research from September 2020 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics Research Recap September 2020

September 2020 psychedelic research looked at the increased neuronal growth (flexibility in the brain) that psychedelics elicit

Psychedelics News September 2020

One psychedelics company reaches the 3-comma club, another releases the second large app. Psychedelics can help with pain, demoralization (for AIDS survivors),

Psychedelics Research Links August 2020

Links to all other psychedelic research from August 2020 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics Research Recap August 2020

Psychedelic research slowed down a bit during this August 2021 | The effect of 20 µg LSD on increasing pain tolerance was widely reported

Psychedelics News August 2020

News about psychedelics hasn't slowed down a bit during August. Everyone was delighted by the news that MAPS raised the $30 million they need to get MDMA-assist

Psychedelics Research Recap July 2020

July 2020 study compares ketamine unfavourably to ECT | Psychedelics for anxiety disorder & psilocybin specifically for OCD

Psychedelics Research Recap June 2020

Psychedelic trials are getting larger in June 2020 | Long-term follow-up of Phase II MDMA for PTSD still showing benefits

Psychedelics Research Links July 2020

Links to all other psychedelic research from July 2020 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics News July 2020

This month starts with a feature of Psychedelic Science Review which has ramped up their reporting and translation of scientific papers to understandable blogs.

Psychedelics News June 2020

As the world is still in partial lockdown, the psychedelics field seems to be evolving quicker than ever before. Much of the news below is related to the plans

Psychedelics Research Links June 2020

Links to all other psychedelic research from June 2020 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics News May 2020

May has been a busy month. One that saw more continued investments, a call for an ethics guide, and interesting results from the largest DMT survey to this date

YouTube and Psychedelics

An overview of psychedelic youtube channels | A focus on psychedelic research (and implementation) and business

Psychedelics Research Links May 2020

Links to all other psychedelic research from May 2020 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics Research Recap May 2020

May 2020 psychedelic research on alcoholism & psychedelics in animals | Research into our brainwaves (with DMT and LSD)

Psychedelics Research Recap April 2020

April has been a slow month for psychedelic research | Microdosing psychedelics remains interesting, yet not studied in a very controlled way

Thoughts on Medicalisation

In the implementation of psychedelics as medicine, the implemenation is key | Medicalisation will become a reality soon

Psychedelics Research Links April 2020

Links to all other psychedelic research from April 2020 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics News April 2020

Psilocybin has been made in yeast in the lab, which could mean even easier (and more accessible) production and distribution of it in the future. A lot of compa

Psychedelics Certification

Find where you can get certification as a psychedelic therapist, practitioner, or coach | Discover who is offering training

Psychedelics Research Recap March 2020

New evidence for psychedelics in the fight against depression | Classical psychedelics seem to be longer-lasting than ketamine

How Big is the Truffles Industry in The Netherlands – Worldwide Predictions

These detailed calculations estimate the value of the psychedelic truffle industry in the Netherlands and worldwide to be...

Psychedelics and SSRIs – What do we know?

Can psychedelics replace SSRIs? What is it that serotonin reuptake inhibitors (SSRIs) do? What is different about psychedelics?

Psychedelics Research Links March 2020

Links to all other psychedelic research from March 2020 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics News March 2020

Although we all want to move the field forward, the two first articles highlight problems going forward. Companies are still making waves and MindMed goes publi

Psychedelics Research Recap February 2020

Psychedelics may not be ready to be accepted by the FDA | The use of psilocybin has positive effects one month later

Psychedelics Research Recap January 2020

This very first psychedelic research analysis by Blossom features two outstanding papers on psychedelics that were published in January 2020

Psychedelics Research Links February 2020

Links to all other psychedelic research from February 2020 | The papers that didn't make it into the psychedelic research database (yet)

Psychedelics News February 2020

This month brought news about microdosing, investments in psychedelics startups, and a very high macro-dose.

Psychedelic Documentaries and Films

A non-complete list of documentaries and other films or series about psychedelics | Explore the stories behind psychedelics

Psychedelics News January 2020

Another exciting month in which there was a lot of reporting on the new FDA approvals (for Compass, Eleusis). Also news on the long-term follow-up of existentia

Expectations: When You Enter a Psychedelic Experience

What role do expectations play in the experience of psychedelics? The placebo effect and other factors surrounding a trip

Psychedelic Podcasts: What to Listen To?

Recommended psychedelic podcasts | Discover how therapy will be implemented | What research is being done | How you can contribute

Psychedelics News December 2019

Archive of news articles on psychedelics that have come out this month | Catalogue of publications (and research) from this month

Overview of Psychedelics Conferences

Find out where to go next to learn about psychedelics | Meet fellow entrepreneurs and researchers who are building psychedelic medicines

Places to Check for News

Overview of websites & news resources to find the latest on psychedelics | The sources that Blossom relies on

Metabolism of Psilocybin in the Human Body

The body metabolises psilocybin to psilocin in the liver, which receptors it binds to in the brain, and the duration of psychedelic effects

Psychedelics News November 2019

Archive of news articles on psychedelics that have come out this month | Catalogue of publications (and research) from this month

Psychedelics News October 2019

Archive of news articles on psychedelics that have come out this month | Catalogue of publications (and research) from this month

Psychedelics News September 2019

Archive of news articles on psychedelics that have come out this month | Catalogue of publications (and research) from this month

Psychedelics News March 2019

Archive of news articles on psychedelics that have come out this month | Catalogue of publications (and research) from this month

Psychedelics News February 2019

Archive of news articles on psychedelics that have come out this month | Catalogue of publications (and research) from this month

Psychedelics News January 2019

Archive of news articles on psychedelics that have come out this month | Catalogue of publications (and research) from this month

Psychedelics News December 2018

Archive of news articles on psychedelics that have come out this month | Catalogue of publications (and research) from this month

Psychedelics News December 2016

Archive of news articles on psychedelics that have come out this month | Catalogue of publications (and research) from this month