Psychedelic Research Links June 2022

This is all the other psychedelic research that came out in June 2022. These papers don’t (yet) have their own page in our database.

You can find all interesting papers in our Papers Database.

Related Papers

• Cognitive, Mental Health, and Physiological Outcomes of Psychedelic Microdosing: A Quantitative Content Analysis of Reddit’s Microdosing Community (thesis)

• Microdosing Psilocybin: A Narrative Inquiry (thesis)

• Review of potential psychedelic treatments for PTSD (review)

• How dangerous is MDMA? (Norwegian)

• Deaths associated with MDMA in the period 2000–19 (Norwegian)

• Neural mechanisms underlying psilocybin’s therapeutic potential – the need for preclinical in vivo electrophysiology (commentary)

• Psychedelic Therapies at the Crossroads of Trauma and Substance Use: Historical Perspectives and Future Directions, Taking a Lead from New Mexico (review)

• Optimization through a Box–Behnken Experimental Design of the Microwave-Assisted Extraction of the Psychoactive Compounds in Hallucinogenic Fungi (Psylocibe cubensis) (extraction method)

• Pharmacological Action of LSD (review)

• If the doors of perception were cleansed, would chronic pain be relieved? Evaluating the benefits and risks of psychedelics (review)

• Extracorporeal Membrane Oxygenation Support in Refractory Multi-organ Failure by 3,4-Methylenedioxymethamphetamine Intoxication (“Ecstasy”) (case study)

• Psychedelic Psychiatry (review)

• A review on the mitochondrial toxicity of “ecstasy” (3,4-methylenedioxymethamphetamine, MDMA) (review)

• Use of intranasal esketamine in a girl with treatment-resistant depression and autism spectrum disorders (case study)

• Rapid and sustained restoration of astrocytic functions by ketamine in depression model mice (rodent study)

• Optimization through a Box–Behnken Experimental Design of the Microwave-Assisted Extraction of the Psychoactive Compounds in Hallucinogenic Fungi (Psylocibe cubensis) (extraction method)

• MDMA for the Treatment of Negative Symptoms in Schizophrenia (review)

• Motives for the use of serotonergic psychedelics: A systematic review (review)

• Polydopamine-based molecularly imprinted electrochemical sensor for highly selective determination of ecstasy components (chemistry)

• Mysticizing medicine: incorporating nondualism into the training of psychedelic guides (opinion)

• Translational control by ketamine and its implications for comorbid cognitive deficits in depressive disorders (in vitro study)

• Pharmacological Management of Nightmares Associated with Posttraumatic Stress Disorder (review)

• Spatiotemporal Mapping of Online Interest in Cannabis and Popular Psychedelics before and during the COVID-19 Pandemic in Poland (survey)

• Effects of stress on endophenotypes of suicide across species: A role for ketamine in risk mitigation (review)

• Sex-specific effects of psychedelics on prepulse inhibition of startle in 129S6/SvEv mice (rodent study)

• ‘Everybody’s creating it along the way’: ethical tensions among globalized ayahuasca shamanisms and therapeutic integration practices (opinion)

• On the third day . . .: The death and resurrection of the study of religious experience (“the present article charts the history of the psychology of religious experiences from the work of founding figures in academic psychology through to the present day“)

• Ayahuasca comes to the city! (essay, the use of ayahuasca in Bogotá) 

• Putative Mechanisms Underlying the Antidepressant Actions of Ketamine: A Review and Study Proposal (thesis)

• Mystical experiences without mysticism: An argument for mystical fictionalism in psychedelics (opinion)

• Effects of acute lysergic acid diethylamide on intermittent ethanol and sucrose drinking and intracranial self-stimulation in C57BL/6 mice (rodent study)

• Preface to the special issue “Psychedelics and Neurochemistry” (preface)

• Repeated subcutaneous racemic ketamine in treatment-resistant depression: case series (case series)

• Physical Disability and Psychedelic Therapies: An Agenda for Inclusive Research and Practice (recommendations for disability inclusion in psychedelic research)

• Effect of Psilocybin and Ketamine on Brain Neurotransmitters, Glutamate Receptors, DNA and Rat Behavior (rodent study)

• Of pharmakon: Hallucination in Amerindian perspectivism and speculative materialism (theory building)

• Serotonergic psychedelic treatment for obesity and eating disorders: potential expectations and caveats for emerging studies (review)

• Validation of the forced swim test in Drosophila, and its use to demonstrate psilocybin has long-lasting antidepressant-like effects in flies (study in flies)

• Effects of acute lysergic acid diethylamide on intermittent ethanol and sucrose drinking and intracranial self-stimulation in C57BL/6 mice (rodent study)

• Invisible wounds: Suturing the gap between the neurobiology, conventional and emerging therapies for posttraumatic stress disorder (review)

• From Underground to Mainstream: Establishing a Medical Lexicon for Psychedelic Therapy (non-stigmatizing terminology in psychedelic research)

• Application of machine learning and complex network measures to an EEG dataset from DMT experiments (“findings supports the idea that cortical brain activity becomes more entropic under psychedelics“)

• Psilocybin for Trauma-Related Disorders (review)

• Psychedelics as preventive treatment in headache and chronic pain disorders (review)

• Novel ethical and policy issues in psychiatric uses of psychedelic substances (commentary)

• Effects of intranasal (S)-ketamine on Veterans with co-morbid treatment-resistant depression and PTSD: A retrospective case series (case series)

• Applying Lessons From Cannabis to the Psychedelic HighwayBuckle Up and Build Infrastructure (commentary)

• Psychedelic-Assisted Therapy for Youth and What We Know From Adult Studies (review)

• Cyberdelics: Context engineering psychedelics for altered traits (conference presentation abstract)

• Esketamine for Unipolar Major Depression With Psychotic Features: A Retrospective Chart Review and Comparison With Nonpsychotic Depression (review)

• Chemical Characterization and Molecular Dynamics Simulations of Bufotenine by Surface-Enhanced Raman Scattering (SERS) and Density Functional Theory (DFT) (chemical characterization of 5-MeO-DMT)

• Classic and non-classic psychedelics for substance use disorder: a review of their historic, past and current research (review)

• Quantum chemical study of the hydrolysis of oxidized endogenous psychedelic N,N-dimethyltryptamine (chemical analysis of DMT)

• Should Adolescents be Included in Emerging Psychedelic Research? (commentary)

• Three Naturally-Occurring Psychedelics and Their Significance in the Treatment of Mental Health Disorders (review)

• Methylenedioxymethamphetamine (MDMA)-Assisted Therapy in Hawaii: A Brief Review (review)

• Meeting Sessions Discuss the Mechanisms and Necessity of Psychedelic ‘Tripping’ (APA conference proceedings)

• Modulation of DNA methylation and protein expression in the prefrontal cortex by repeated administration of D-lysergic acid diethylamide (LSD): Impact on neurotropic, neurotrophic, and neuroplasticity signalling (rodent study)

• Brain Wellness “Spas”—Anticipating the Off-label Promotion of Psychedelics (commentary)

• Psychedelic Sociality: Pharmacological and Extrapharmacological Perspectives (editorial)

• β-carboline-independent antidepressant-like effect of the standardized extract of the barks of Mimosa tenuiflora (Willd) Poir. occurs via 5-HT2A/2C receptors in mice (Mimosa tenuifora (SEMT) – another DMT-containing beverage showed antidepressant effects in mice)

• Amitriptyline Accelerates SERT Binding Recovery in a Rat 3,4-Methylenedioxymethamphetamine (MDMA) Model: In Vivo 4-[18F]-ADAM PET Imaging (in rats, amitriptyline (tricyclic antidepressants) is possibly neuroprotective/helps recovery)

• Ketamine Assisted Psychotherapy: A Systematic Narrative Review of the Literature (review, “findings suggest psychotherapy, provided before, during, and following ketamine sessions, can maximize and prolong benefits“)

• Optimization through a Box-Behnken Experimental Design of the Microwave-Assisted Extraction of the Psychoactive Compounds in Hallucinogenic Fungi ( Psylocibe cubensis) (psilocybin extraction)

• Metabolomic signatures of intravenous racemic ketamine associated remission in treatment-resistant depression: A pilot hypothesis generating study (n=9, iv ketamine, new hypothesis about mechanisms of action)

• Guanosine as a promising target for fast-acting antidepressant responses (review, guanosine as a possible alternative or adjunct to ketamine treatment)

• Mitochondrial DNA methylation profiling of the human prefrontal cortex and nucleus accumbens: correlations with aging and drug use (correlation is not causation, but ketamine users had ‘older’ epigenetic clocks than non-illicit drug users)

• Psychoactive Drugs in the Management of Post Traumatic Stress Disorder: A Promising New Horizon (opinion)

• Montgomery-Åsberg Depression Rating Scale factors in treatment-resistant depression at onset of treatment: Derivation, replication, and change over time during treatment with esketamine (analysis of earlier data, shows 3 factors of depression scale (MADRS; all improved) in esketamine trials)

• The Potential of Psychedelics in the Treatment of Drug Addiction in Animal Models (thesis)

• Psychedelic-assisted psychotherapy to treat psychiatric and existential distress in life-threatening medical illnesses and palliative care (review)

• Classic and non‐classic psychedelics for substance use disorder: A review of their historic, past and current research (review)

• LSD and perception: The Bergson–Gibson model for direct perception and its biochemical framework (hypothesis generation)

• Mapping consent practices for outpatient psychiatric use of ketamine (real-world data on consent before ketamine treatment)

• Stairway to Heaven A First-Person Account of Noesis (first-person, though academic, description of psychedelic experience)

• The Lived Experiences of an Exemplar Woman Medium Using Ayahuasca for Healing: A Qualitative Research Study (thesis)

• Psychedelic integration: An analysis of the concept and its practice (conceptual analysis)

• Evaluating 5-Methoxy-N,N-Dimethyltryptamine as a Potential Treatment for Neuropsychiatric Disorders (to be published)

• (R)-ketamine as prophylactic and therapeutic drug for neurological disorders: Beyond depression (review, possibility of ketamine to prevent neurological disorders (e.g. Parkinson’s))

• Classic Psychedelics and Human–Animal Relations (n=2822, survey data, showed positive correlation between animal solitary & lower speciesism, but not on desire to help animals for those who use psychedelics)