Diterpenoid

Salvia Divinorum

A specialized plant species that produces salvinorin A, a potent and selective kappa-opioid agonist with intense, short-lived effects.

Pharmacology & Mechanism of Salvia Divinorum

Detailed pharmacological information is currently being assembled by our research team.

Quick Facts

  • Highest PhaseNo trials listed yet
  • Primary MechanismKappa Opioid Receptor (KOR) Agonist
  • Session Duration15-60 minutes
  • OriginBotanical

Connected Research

Recent clinical trials and academic literature investigating Salvia Divinorum.

Recent Academic Papers

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Acute Effects of Hallucinogens on Functional Connectivity: Psilocybin and Salvinorin-A

Published
Journal
ACS Chemical Neuroscience

Among psychedelic-experienced users, only past use of psilocybin reliably predicts nature relatedness

Published
Journal
Journal of Psychopharmacology

The kappa opioid receptor and the sleep of reason: Cortico-subcortical imbalance following salvinorin-A

Published
Journal
International Journal of Neuropsychopharmacology

DARK Classics in Chemical Neuroscience: Salvinorin A

Published
Journal
ACS Chemical Neuroscience

The Acute Effects of the Atypical Dissociative Hallucinogen Salvinorin A on Functional Connectivity in the Human Brain

Published
Journal
Scientific Reports

Salvia divinorum: from recreational hallucinogenic use to analgesic and anti-inflammatory action

Published
Journal
Journal of Pain Research