American Samoa

Reimbursed Care Access

American Samoa treats most classic psychedelics (psilocybin, MDMA, DMT, 5‑MeO‑DMT, ibogaine, ayahuasca, mescaline, 2C‑X) as controlled/hallucinogenic substances with criminal penalties and no routine medical access outside of approved research. FDA‑approved prescription products that are controlled (e.g., esketamine/SPRAVATO and medically‑authorized ketamine for anesthesia) may be available under U.S. federal regulatory frameworks, but territory Medicaid and reimbursement arrangements are administered under territory‑specific rules and can be more restrictive than U.S. states; coverage for high‑cost REMS medicines or off‑label psychedelic therapies is limited and usually requires prior authorization or referral off‑island.