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Psychedelic Therapy Access in Europe: Comparison

Compare ketamine and esketamine licensing, reimbursement, and patient access pathways across selected European markets.

17 April 2026

Europe access comparison

This resource provides a side-by-side view of ketamine and esketamine access pathways across selected European markets, with a focus on licensing status, reimbursement, and practical availability.

Psychedelic Therapy Access in Europe

Detailed comparison of ketamine and esketamine licensing, reimbursement status, and patient access across selected European markets.

Germany

Ketamine

Licensed:No

No statutory health insurance coverage; individual reimbursement applications via insurers.

Very limited (individual hospitals).

Esketamine (Spravato)

Licensed:Yes

Reimbursed; positive HTA outcome (G-BA/IQWiG).

Limited, but expanding.

United Kingdom

Ketamine

Licensed:No

No national reimbursement status or routine NHS funding.

Very limited (private clinics, select NHS trusts).

Esketamine (Spravato)

Licensed:Yes

Not recommended in England and Wales (NICE); recommended in Scotland (SMC).

Extremely limited in England and Wales; private clinic access available.

Netherlands

Ketamine

Licensed:No

Insurance coverage for clinical support costs.

Limited, but expanding.

Esketamine (Spravato)

Licensed:Yes

Approved for coverage under basic health insurance (2021).

Very limited (few dozen patients yearly).

Czech Republic

Ketamine

Licensed:No

Some insurance coverage with patient co-payment.

Established clinical access since 2020.

Esketamine (Spravato)

Licensed:Yes

Exceptional reimbursement for TRD; standard reimbursement approved at end of 2024.

Limited, but expanding with major insurance coverage.

Source: Reimbursement Pathways for Psychedelic Therapies in Europe (Report)

How to use this comparison

  • Use this table as a market-scoping reference when prioritising evidence, payer, and service-readiness planning.
  • Re-validate entries before publication decisions, as reimbursement conditions can change quickly across jurisdictions.