Psilocybin reduced neural responses to surprising tactile stimuli, decreasing activity in frontal regions, visual cortex and cerebellum and attenuating frontal tactile mismatch negativity, consistent with aberrant prediction‑error processing and 5‑HT2A‑mediated disruption of bodily‑self integration. These findings link altered tactile deviancy processing to changes in self‑experience and suggest relevance for psychiatric disorders characterised by aberrant bodily self‑awareness.
- Published
- Journal
- Cerebral Cortex
- Authors
- Duerler, P., Brem, S., Fraga-González, G., Neef, T., Allen, M., Zeidman, P., Stämpfli, P., Vollenweider, F. X., Preller, K. H.