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Academic JournalOpen Access

Journal of Clinical Medicine

2 Papers Indexed in Blossom

Published Papers

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MDMA for the Treatment of Negative Symptoms in Schizophrenia

This review argues that MDMA‑assisted therapy is a promising novel approach for treating negative symptoms of schizophrenia, drawing on MDMA’s prosocial, empathogenic and metaplastic effects to target deficits for which there are currently no FDA‑approved treatments. It synthesises recent evidence suggesting MDMA may be safe and potentially effective and outlines safety considerations and putative mechanisms of action.

Published
Journal
Journal of Clinical Medicine
Authors
Arnovitz, M. D., Spitzberg, A. J., Davani, A. J., Vadhan, N. P., Holland, J., Kane, J. M., Michaels, T. I.
Open Accessmeta

Trajectory of Antidepressant Effects after Single- or Two-Dose Administration of Psilocybin: A Systematic Review and Multivariate Meta-Analysis

This review & meta-analysis (s=10, n=226) finds that two (vs one) sessions and a higher dose of psilocybin (up to 30mg) were associated with better antidepressant effects. The meta-analysis showed a robust antidepressant effect up to 6 months later (d = -1.12).

Published
Journal
Journal of Clinical Medicine
Authors
Yu, C. L., Liang, C. S., Yang, F., Tu, Y. K., Hsu, C. W., Carvalho, A. F., Stub, B., Thompson, T., Tsai, C. K., Yeh, T. C., Yang, S. N., Shin, J. I., Chu, C. S., Tseng, P. T., Su, K. P.

Quick Facts

Papers Indexed
2
h-Index
132
Open Access
Yes
Publisher
MDPI
Country
Switzerland
Website
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