This case study (2019) explores repeated intravenous (IV) ketamine in synergy with antidepressants to treat refractory depression (TRD). It found that high-dose IV ketamine may stably enhance depressive symptoms and cognitive function in patients with TRD who do not tend to respond to a rapid intravenous dose of standard-dose ketamine.
- Published
- Journal
- Journal of Clinical Pharmacy and Therapeutics
- Authors
- Wang, L., Wang, M., Xiong, Z., Yang, Y., Li, Z., Su, B.