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Academic Journal

Medical Hypotheses

6 Papers Indexed in Blossom

Published Papers

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The potential use of N-methyl-3,4-methylenedioxyamphetamine (MDMA) assisted psychotherapy in the treatment of eating disorders comorbid with PTSD

This hypothesis paper (2020) makes the case for treating eating disorders (EDs) comorbid with posttraumatic stress disorder (PTSD).

Published
Journal
Medical Hypotheses
Authors
Brewerton, T. D., Lafrance, A., Mithoefer, M. C.
Open Accessindividual

Psychedelic medicine: The biology underlying the persisting psychedelic effects

This paper presents an alternative hypothesis of how psychedelics work with a focus on sleep (macrodose) and the microbiome (microdose). The author proposes ways of testing this hypothesis.

Published
Journal
Medical Hypotheses
Authors
Kuypers, K. P. C.
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Out of the box: A psychedelic model to study the creative mind

This hypothesis article (2018) proposes a psychedelic model to study the creative mind. Kuypers goes into depth on the brain structures and processes influenced by psychedelics.

Published
Journal
Medical Hypotheses
Authors
Kuypers, K. P. C.
Open Accessmeta

The fibrinolytic system: A new target for treatment of depression with psychedelics

This hypothesis-building article (2017) proposes that psychedelics such as psilocybin and ketamine exert antidepressant effects by restoring balance to the fibrinolytic system, a network of enzymes in the bloodstream that prevent blood clots from growing and reopen vessels closed by thrombosis. The authors postulate that psilocybin decreases coagulation promoting factors, neuroinflammation, and fibrin deposition in the brain, and restores the 5-HT2a receptor to pre-stress levels.

Published
Journal
Medical Hypotheses
Authors
Idell, R. D., Florova, G., Komissarov, A. A., Shetty, S., Girard, R. B. S., Idell, S.
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Endogenous hallucinogens as ligands of the trace amine receptors: A possible role in sensory perception

This theory-building paper (2009) proposes that endogenous hallucinogen trace amine receptors (not serotonin 2A receptors) mediate the visual altering effects of psychedelics.

Published
Journal
Medical Hypotheses
Authors
Wallach, J. V.
Open Accessmeta

Endogenous psychoactive tryptamines reconsidered: an anxiolytic role for dimethyltryptamine

This early review (2005) suggests that the effects of exogenous DMT may be due at least in part to activity at the trace amine receptor.

Published
Journal
Medical Hypotheses
Authors
Jacob, M. S., Presti, D. E.

Quick Facts

Papers Indexed
6
h-Index
112
Open Access
No
Publisher
Elsevier
Country
United Kingdom
Website
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