This mega-analysis integrated 11 resting-state MRI datasets on acute effects of psilocybin, lysergic acid diethylamide, mescaline, N,N-dimethyltryptamine and ayahuasca, and found that psychedelics commonly increased connectivity between higher-order and sensory brain networks. It also found altered links involving the thalamus, caudate, putamen and cerebellum, with only modest and variable reductions within networks.
- Published
- Journal
- Nature Medicine
- Authors
- Girn, M., Doss, M. K., Roseman, L., Preller, K. H., Palhano-Fontes, F., Pasquini, L., Barrett, F. S., Mallaroni, P., Mason, N. L., Timmermann, C., McCulloch, D. E., Fisher, P. M., Winston, B. S., Moujaes, F., Muller, F., Liechti, M. E., Vollenweider, F. X., Ramaekers, J. G., Kuypers, K., Araujo, D. B., Sporns, O., Siegel, J., Dosenbach, N., Nutt, D. J., Carhart-Harris, R. L., Stamatakis, E. A., Bzdok, D.