Using LORETA on EEG from 18 volunteers given encapsulated ayahuasca (0.85 mg DMT/kg), the study found significant decreases in alpha‑2, delta, theta and beta‑1 power 60–90 minutes after dosing versus placebo. These reductions were localised to the temporo‑parieto‑occipital junction and temporomedial/frontomedial regions, paralleled increased Hallucinogen Rating Scale scores, and implicate unimodal/heteromodal association cortices and limbic structures in ayahuasca’s psychological effects.
- Published
- Journal
- Neuropsychobiology
- Authors
- Riba, J., Anderer, P., Jané, F., Saletu, B., Barbanoj, M. J.