This randomised, double-blind, placebo-controlled trial protocol and pilot study (n=42) is testing ketamine 0.5 mg/kg given under propofol sedation for chronic pain with depression, with pain as the main outcome. In six pilot participants, there were no serious adverse events and propofol seemed to help mask treatment allocation, although many still guessed ketamine immediately after sedation.
- Published
- Journal
- Pain Management
- Authors
- Lii, T. R., Sikka, P., Deverett, B., Altirkawi, O. K., Heifets, B. D.