The authors developed and validated a simple gas chromatographic method (solid‑phase C18 extraction, N/P detection) for simultaneous quantification of N,N‑dimethyltryptamine and the main β‑carbolines in ayahuasca, with an LLOQ of 0.02 mg/mL, linearity to 4.0 mg/mL (r2>0.99) and RSD <10%. The assay permits reliable estimation of administered doses in animals and humans for subsequent pharmacological and toxicological studies.
- Published
- Journal
- Phytochemical Analysis
- Authors
- Pires, A. P. S., De Oliveira, C. D. R., Moura, S., Dörr, F. A., Silva, W. A. E., Yonamine, M.