This double-blind trial (n=14) compared the effects of MDMA (52.5-105 mg/70kg), intranasal oxytocin (20 IU or 40 IU), and placebo on plasma oxytocin concentrations. MDMA (105 mg/70kg only) increased plasma oxytocin levels to a mean peak of 83.7 pg/ml at approximately 90-120 min compared to a 48.0 pg/ml, 30-60 min increase after oxytocin administration.
- Published
- Journal
- Psychoneuroendocrinology
- Authors
- Kirkpatrick, M. G., Francis, S. M., Lee, R., de Wit, H., Jacob, S.