Outcome MeasureMystical Experience

11D-ASC

Eleven Dimensions of Altered States of Consciousness

2 Papers in Blossom

About This Instrument

The Eleven Dimensions of Altered States of Consciousness (11D-ASC) is an updated factorial structure derived from the same 94 visual analog scale items as the 5D-ASC. Proposed by Erich Studerus and colleagues through confirmatory factor analysis, the 11 dimensions provide more differentiated subscales: Experience of Unity, Spiritual Experience, Blissful State, Insightfulness, Disembodiment, Impaired Control and Cognition, Anxiety, Complex Imagery, Elementary Imagery, Audio-Visual Synesthesia, and Changed Meaning of Percepts. This finer-grained structure better captures the multidimensional nature of psychedelic experiences and allows researchers to correlate specific experiential dimensions with therapeutic outcomes. The 11D-ASC is increasingly preferred over the original 5D structure in modern psychedelic clinical trials because it separates positive mystical elements from perceptual phenomena and differentiates anxiety from cognitive impairment.

Outcome Data Across Studies

Reported results for 11D-ASC across 2 studies with quantitative data.

Outcome data across 4 study arm–timepoint observations
				SD
A qualitative and quantitative account of patient’s experiences of ketamine and its antidepressant properties 2021Primary	Ketamine(experimental)	32	28.5	16.9	—
A qualitative and quantitative account of patient’s experiences of ketamine and its antidepressant properties 2021Primary	Remifentanil(active_comparator)	30	5.5	7.6	—
Enhanced visual contrast suppression during peak psilocybin effects: Psychophysical results from a pilot randomized controlled trial 2024Secondary	Psilocybin first(experimental)	6	55.0	29.4	—
Enhanced visual contrast suppression during peak psilocybin effects: Psychophysical results from a pilot randomized controlled trial 2024Secondary	Niacin first(experimental)	6	2.0	4.9	—

Papers Using 11D-ASC

Open Accessindividual

Enhanced visual contrast suppression during peak psilocybin effects: Psychophysical results from a pilot randomized controlled trial

This placebo-controlled study (n=6) investigates how psilocybin (25mg) affects visual surround suppression compared to placebo (100mg niacin). The study finds increased surround suppression effects under psilocybin, with stronger suppression correlating with more intense subjective visual effects.

Published: November 5, 2024
Journal: Journal of Vision
Authors: Swanson, L. R., Jungers, S., Varghese, R., Cullen, K. R., Evans, M. D., Nielson, J. L., Schallmo, M.-P.

Paywallindividual

A qualitative and quantitative account of patient’s experiences of ketamine and its antidepressant properties

In 32 people with major depressive disorder given subanaesthetic ketamine versus an active placebo, larger 24‑hour antidepressant responses correlated with psychedelic dimensions (spirituality, unity, insight) and qualitative interviews documented pervasive perceptual changes, loss of control, emotional shifts and a lasting afterglow that altered perspectives on life and treatment. These findings give preliminary evidence that the acute psychedelic experience and afterglow contribute to ketamine’s antidepressant effects and that common questionnaires may not fully capture its phenomenology.

Published: March 30, 2021
Journal: Journal of Psychopharmacology
Authors: Sumner, R. L., Chacko, E., Mcmillan, R., Spriggs, M. J., Anderson, C., Chen, J., French, A., Jung, S., Rajan, A., Malpas, G., Hay, J., Ponton, R., Muthukumaraswamy, S. D., Sundram, F.

Quick Facts

Full Name: Eleven Dimensions of Altered States of Consciousness
Domain: Mystical Experience
Papers Indexed: 2
Score Range: 0–100
Interpretation: Higher = better
Unit: percentage

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