Outcome MeasureSubstance Use

ASI

Addiction Severity Index

1 Paper in Blossom

Clinical Thresholds

01
No problem
Score 0–0.19
Slight problem
Score 0.2–0.39
Moderate problem
Score 0.4–0.59
Considerable problem
Score 0.6–0.79
Extreme problem
Score 0.8–1

Outcome Data Across Studies

Reported results for ASI across 1 study with quantitative data.

Outcome data across 1 study arm–timepoint observations
SD
Safety of ibogaine administration in detoxification of opioid dependent individuals: a descriptive open-label observational study
2021Secondary
Ibogaine single dose(experimental)0141.01.2—

Papers Using ASI

Open Accessindividual

Safety of ibogaine administration in detoxification of opioid dependent individuals: a descriptive open-label observational study

This open‑label study (n=14) of opioid‑dependent patients given a single 700 mg per 70kg dose of ibogaine‑HCl, treatment produced clinically relevant but reversible cardiac and cerebellar toxicity. The mean maximal QTc(F) prolongation was 95 ms, with 50% of participants exceeding 500 ms, accompanied by bradycardia and severe transient ataxia. Psychomimetic and withdrawal effects were generally manageable, and no torsades de pointes were observed.

Published
Journal
Addiction
Authors
Knuijver, T., Schellekens, A., Belgers, M., Donders, R., Kramers, C., Verkes, R. J.

Quick Facts

Full Name
Addiction Severity Index
Domain
Substance Use
Papers Indexed
1
Score Range
0–1
Interpretation
Lower = better
Unit
composite score
All Measures