Outcome MeasureMystical Experience

PSI

Psychedelic-Specific Insight Scale

2 Papers in Blossom

Outcome Data Across Studies

Reported results for PSI across 2 studies with quantitative data.

Outcome data across 5 study arm–timepoint observations
SD
Ketamine Modulates the Neural Correlates of Reward Processing in Unmedicated Patients in Remission from Depression
2022Secondary
Ketamine 0.5mg/kg(experimental)03748.422.90.050
Ketamine Modulates the Neural Correlates of Reward Processing in Unmedicated Patients in Remission from Depression
2022Secondary
Placebo(placebo)03715.110.50.050
Magnesium-ibogaine therapy in veterans with traumatic brain injuries
2024Exploratory
Ibogaine + magnesium(experimental)03053.810.6—
Magnesium-ibogaine therapy in veterans with traumatic brain injuries
2024Exploratory
Ibogaine + magnesium(experimental)13059.29.7—
Magnesium-ibogaine therapy in veterans with traumatic brain injuries
2024Exploratory
Ibogaine + magnesium(experimental)302761.610.7—

Papers Using PSI

Open Accessindividual

Magnesium-ibogaine therapy in veterans with traumatic brain injuries

This observational study (n=30) evaluates ibogaine (up to 980mg/70kg) in combination with magnesium (1-2 hours before and 12 hours later) in male Special Operations Forces veterans with predominantly mild traumatic brain injury (mTBI). The study assessed changes in disability, PTSD, depression, and anxiety immediately and one month after treatment using various scales. Results show significant improvements in functioning and psychological symptoms with no serious adverse events.

Published
Journal
Nature Medicine
Authors
Cherian, K. N., Keynan, J. N., Anker, L., Faerman, A., Brown, R. E., Shamma, A., Keynan, O., Coetzee, J. P., Batail, J. M., Phillips, A., Bassa, N. J., Sahlem, G. L., Inzunza, J., Millar, T., Dickinson, J., Rol, C. E., Keller, J., Adamson, M., Kratter, I. H., Williams, N. R.
Open Accessindividual

Ketamine Modulates the Neural Correlates of Reward Processing in Unmedicated Patients in Remission from Depression

This double-blind, placebo-controlled study (n=37) found that ketamine improved responses to rewards two hours after depressed patients had received ketamine (35mg/70kg) treatment. This correlated with neurological observations (increases in activation of NAc, the putamen, the insula, and the caudate).

Published
Journal
Biological Psychiatry
Authors
Kotoula, V., Stringaris, A., Mackes, N., Mazibuko, N., Hawkins, P. C. T., Furey, M., Curran, V., Mehta, M. A.

Quick Facts

Full Name
Psychedelic-Specific Insight Scale
Domain
Mystical Experience
Papers Indexed
2
Interpretation
Higher = better
All Measures