LSD

Influence of Lysergic Acid Diethylamide (LSD-25) on Subjective Time

This open-label within-subjects design study (n=24) investigated the effects of LSD (75-150μg) on time perception. Participants were assigned time intervals (15, 60, 120, and 240 minutes) and asked to indicate when the time had elapsed; participants provided shorter times estimates under the influence of LSD, indicating that subjective time elapsed more rapidly compared to the control condition.

Authors

  • Aronson, H.
  • Silverstein, A. B.
  • Klee, G. D.

Published

JAMA Psychiatry
individual Study

Abstract

Introduction

Various reports have shown that the subjective sense of time can be considerably altered through changes in the external circumstances under which the judgment is made. Somewhat less is known of the influence of the subject’s physical state on his ability to estimate time. This lack may be at least partially due to the fact that most conditions, such as fever or delirium, which have been described as bringing about such changes often simultaneously make it difficult or impossible to collect systematic data. When physical states are experimentally induced, however, the effects can be better controlled and tested. In this way, information has been obtained on the influence of nitrous oxide and mescaline on the sense of time. The very striking effect of lysergic acid diethylamide (LSD-25) on the sense of time has been described in various ways by those who have observed the reaction: Time sense . . . was characterized by the feeling of being accelerated or retarded ; Not only is there impaired ability to estimate the passage of time, but there is also a sense of timelessness.

Methods

Twenty-four subjects were used as their own controls to determine the effect of lysergic acid diethylamide (LSD-25) on the subjective passage of time.

Results

Under the drug the subjects overestimated the stimulus intervals to a significant degree, indicating that the drug has the effect of making time appear to pass more slowly than usual.

Discussion

The results of this study were unlike those reported in an earlier experiment, in which no consistent changes were found under the drug. Differences between experimental procedures were discussed to suggest reasons for the divergent results. The findings were examined for theoretical implications in light of other changes noted as common to the LSD-25 reaction.

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Research Summary of 'Influence of Lysergic Acid Diethylamide (LSD-25) on Subjective Time'

Introduction

Earlier reports have shown that people’s subjective sense of time can change markedly with external circumstances, and a smaller literature has examined how a person’s physical state alters time estimation. Clinical conditions such as fever and delirium are difficult to study systematically, but experimentally induced states—using agents such as nitrous oxide or mescaline—have provided more controlled evidence that perception of time can be altered. Lysergic acid diethylamide (LSD-25) has been described in observational reports as producing striking temporal distortions, including feelings of acceleration, retardation, or timelessness, but at least one systematic study had reported only increased variability without a directional shift in estimates. Aronson and colleagues designed an experimental study to test whether LSD-25 produces a consistent directional change in subjective time judgment under controlled conditions. The study aimed to compare time estimates made under LSD-25 with those made in the normal state, using a within-subjects design to reduce between-subject variability and to clarify discrepancies in the earlier literature.

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Study Details

  • Study Type
    individual
  • Journal
  • Compound
  • APA Citation

    ARONSON, H. (1959). Influence of Lysergic Acid Diethylamide (LSD-25) on Subjective Time. Archives of General Psychiatry, 1(5), 469. https://doi.org/10.1001/archpsyc.1959.03590050037003

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