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Pyretogenic effect of lysergic acid diethylamide
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Dille, J. M., Horita, A.
This early (1954) animal study (n=9) investigated the pyrogenic (fever-inducing) properties of LSD (50μg/kg), which produced a rise in body temperature of normal rabbits, cats, and dogs. This rise in temperature which lasted up to 9 hours is antagonized by the administration of sodium pentobarbital but not by antipyrine or adrenergic blocking agents.
Abstract
From the conclusion: Lysergic acid diethylamide produces a rise in body temperature of normal rabbits, cats, and dogs. This rise in temperature is antagonized by the administration of sodium pentobarbital but not by antipyrine or adrenergic blocking agents