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USGrantedDerivative

Substituted alkyl-amine compounds and methods (psychoplastogens)

US-11440879-B2

Bibliographic data

Patent number
US-11440879-B2
Jurisdiction
US
Status
Granted
Type
Derivative
Priority date
18 February 2020
Filing date
25 October 2021
Grant date
13 September 2022

Compounds claimed

DMT
Tryptamine
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Assignees

Gilgamesh Pharma
Gilgamesh Pharma Inc. is the post-spinoff successor of Gilgamesh Pharmaceuticals, created in October 2025 when AbbVie acquired Gilgamesh's lead asset bretisilocin (GM-2505) for up to $1.2B. Launched with over $100M in funding and retaining the original team, Gilgamesh Pharma is advancing a pipeline of rapid-acting, durable psychiatric therapeutics including blixeprodil (GM-1020), a first-in-class oral NMDA receptor antagonist. Positive Phase 2a data for blixeprodil were announced January 6, 2026, and late-stage development is planned for 2026. The company also retains an ongoing AbbVie collaboration on non-hallucinogenic neuroplastogens.
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