Rodrigo Mansur

R. B. Mansur is a clinician–researcher working at the intersection of psychedelic-assisted therapies and rapid-acting pharmacological treatments for mood disorders. Mansur’s recent portfolio centres on clinical trials and real-world studies of psilocybin-assisted psychotherapy for treatment-resistant depression — including investigations of repeated dosing and applications in individuals with bipolar II disorder — alongside pragmatic evaluations of repeated intravenous ketamine infusions in populations characterised by youth, borderline personality disorder comorbidity, and suicidality. Mansur has also contributed to mechanistic clinical research exploring whether sleep changes mediate the antidepressant and anti-suicidal effects of intravenous ketamine.

Mansur’s work emphasises translational clinical design and real-world effectiveness, addressing important clinical questions about safety, applicability across diagnostic comorbidity, dosing strategies, and short-term mechanistic mediators of response. These contributions support the evidence base for integrating psychedelic and rapid-acting interventions into treatment pathways for people with treatment-resistant depressive disorders and complex psychiatric comorbidity.