Simon Ruffell
Psychiatrist and psychedelic researcher; Senior Research Associate at King's College London / affiliated with Onaya Science
Data updated
Research Footprint
Simon Ruffell appears in 7 tracked papers (2021–2025), most studied alongside Ayahuasca, Psilocybin and LSD, across Depressive Disorders, Anxiety Disorders and PTSD.
Most-cited paper: Default Mode Network Modulation by Psychedelics: A Systematic Review (219 citations).
Frequent co-authors: Daniel Perkins, Joseph Sarris and Robin Carhart-Harris.
Background & Research
Dr Simon G. D. Ruffell is a psychiatrist and psychedelic researcher with a medical background in psychiatry and a research focus on ayahuasca, psilocybin, and mental health outcomes. His work spans naturalistic retreat studies, veteran populations, and broader psychedelic mechanisms, and he has been associated with King's College London and Onaya Science. He has also written and spoken about psychedelic medicine and traditional plant-medicine contexts.
Key Impact
He is notable for leading and coauthoring naturalistic and review studies on ayahuasca and psilocybin, including work on veterans, mental health outcomes, EEG, epigenetics, and the gut-brain axis.
Collaboration Network
16 collaborators· click a node to visit their profile
Full network →Compounds
Topics
Top Collaborators
Affiliations
Institutions, companies, and organisations Simon Ruffell is associated with.
King's College London
academicThe Centre for Mental Health Research and Innovation and the Psychoactive Trials Group are actively conducting clinical trials with various psychedelic compounds to develop new care models for treatment-resistant depression, PTSD, and anorexia nervosa.
View stakeholder →University of Exeter
The University of Exeter is a public research university located in Exeter, England. It operates multiple campuses including Streatham and St Luke’s in Exeter and a campus at Penryn in Cornwall.
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