What happened in psychedelic research in 1970

Week of 28 December 1970

• CompletedSingle Oral Lysergide (LSD 500 µg) in Inpatient Alcoholic Rehabilitation: Controlled Evaluation with Schizophrenic Sub-Anal… (lsd)31 Dec

  This unregistered trial (n=75) was a partially randomised, placebo-controlled evaluation of a single 500 µg oral dose of LSD for alcohol use disorder in an inpatient rehabilitation setting, which found higher abstinence rates in non-schizophrenic participants at one year.

  LSD

  View trial→

Week of 30 November 1970

• PaperLysergide Treatment of Schizophrenic and Nonschizophrenic Alcoholics; A Controlled Evaluation1 Dec

  This historic study (1970; n=75) used LSD (500μg) in the treatment of alcoholics and found that those without schizophrenia (about 2/3 of patients) responded better.

  LSDSchizophreniaAlcohol Use Disorder (AUD)Substance Use Disorders (SUD)

  View paper→

Week of 29 December 1969

• StartedDPT-Assisted Psychedelic-Peak Psychotherapy for Alcoholism: An Open Clinical Study (Grof 1973, Spring Grove State Hospital)1 Jan

  Exploratory, open clinical study (International Pharmacopsychiatry 1973; Grof S, Soskin RA, Richards WA, Kurland AA; Spring Grove State Hospital, Baltimore, MD, USA). Participants: 51 alcoholic patients drawn from the Alcoholic Rehabilitation Unit of Spring Grove State Hospital, selected by medical and psychiatric screening for suitability for psychedelic-peak therapy. Exclusions included organic brain damage, epilepsy, active renal or hepatic disease, and other specified contraindications. Intervention: dipropyltryptamine (DPT), a synthetic short-acting psychedelic, administered as an adjunct to psychotherapy in a psychedelic-peak therapy framework. No control arm; open-label exploratory design. Outcomes: clinical and psychotherapeutic change in alcoholism. No trial registry; pre-dates any formal registration requirement by ~32 years.

  View trial→