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Home/Research/2C-X/Medicinal Chemistry & Drug Development

2C-X for Medicinal Chemistry & Drug Development

2 papers and 0 clinical trials exploring 2c-x as a treatment for medicinal chemistry & drug development.

CompoundPhenethylamine

2C-X

2C-X denotes a family of synthetic phenethylamine psychedelics defined by a 2,5-dimethoxyphenethylamine scaffold. 2C-B is the best-studied member, with emerging controlled human data benchmarking it against psilocybin and MDMA.

Full 2C-X profile
IndicationOver 300 million people worldwide experience depression, with many also suffering from related anxiety disorders.

Medicinal Chemistry & Drug Development

Medicinal chemistry plays a crucial role in the development of novel psychedelic compounds, focusing on their molecular structures and interactions. Researchers utilise innovative methods to enhance safety and efficacy in psychedelic substances.

Full Medicinal Chemistry & Drug Development profile

Academic Research

2 papers
Open Accessindividual

Discovery of G Protein-Biased Antagonists against 5-HT7R

This mouse study explored the effects of a number of synthetic psychoactive drugs, such as the 2C-family, on the serotonin receptor 5-HT7R. The ability of a particular 2C compound to bind 5-HT7R over other subtypes and reduce self-grooming time in mice suggests that 5-HT7R could be a potential target for treating autism.

Published
September 14, 2021
Journal
Journal of Medicinal Chemistry
Authors
Lee, H., Lee, J., Kim, D., Kim, H., Kim, J., Yeom, M., Cho, Y., Keum, G., Jeon, B., Choo, H., Kwang, R.
Paywallmeta

Pharmacology and Toxicology of N-Benzylphenethylamine (“NBOMe”) Hallucinogens

This academic book chapter (2017) reviews the pharmacology and toxicology of N-benzylphenethylamine (NBOMe) hallucinogens (including 2C-B). It found that rhabdomyolysis is a fairly common complication of severe NBOMe toxicity, which can be linked to NBOMe-induced hyperthermia, seizures, and vasoconstriction.

Published
January 18, 2017
Journal
Current Topics in Behavioral Neurosciences
Authors
Halberstadt, A. L.

Clinical Trials

0 trials

No clinical trials have been tagged with both 2C-X and Medicinal Chemistry & Drug Development yet.

Trials are continuously being added as new studies are registered.

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Search all 2C-X papers Search all Medicinal Chemistry & Drug Development trials Full 2C-X profile Full Medicinal Chemistry & Drug Development profile