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Home/Research/Ayahuasca/Neurological Injury

Ayahuasca for Neurological Injury

1 paper and 0 clinical trials exploring ayahuasca as a treatment for neurological injury.

Compoundclassic psychedelic

Ayahuasca

Ayahuasca is a botanical decoction combining DMT with MAO-inhibiting harmala alkaloids, producing intense psychedelic effects lasting 3-6 hours. Clinical trials show rapid, large antidepressant effects from a single dose, with a favourable safety profile in controlled settings.

Full Ayahuasca profile
IndicationApproximately 15 million individuals experience a stroke annually, while traumatic brain injuries occur in around 69 million people worldwide each year.

Neurological Injury

Neurological injury encompasses various forms of brain damage resulting from trauma, strokes, or other factors, leading to significant functional impairment. Recent research into psychedelic compounds presents promising avenues for innovative therapeutic interventions aimed at enhancing recovery and alleviating associated psychological conditions such as PTSD and depression.

Full Neurological Injury profile

Academic Research

1 paper
Open Accessindividual

Exploring the Therapeutic Effects of Psychedelics Administered to Military Veterans in Naturalistic Retreat Settings

Veterans attending naturalistic psilocybin or ayahuasca retreats showed significant improvements across eight mental‑health and reintegration measures, with the largest reductions in depression (PHQ‑9, 29.1%) and PTSD (PCL‑5, 26.1%). Psilocybin retreats produced greater gains on most outcomes while ayahuasca yielded slightly larger PTSD improvement; those with worse baseline symptoms benefited most, with some gender-specific differences.

Published
July 7, 2025
Journal
Brain and Behavior
Authors
Calnan, M., Blest-Hopley, G., Busch, C., Adams, M., Ruffell, S. G. D., Piper, T., Roseman, L., Kettner, H., Carhart-Harris, R.

Clinical Trials

0 trials

No clinical trials have been tagged with both Ayahuasca and Neurological Injury yet.

Trials are continuously being added as new studies are registered.

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Search all Ayahuasca papers Search all Neurological Injury trials Full Ayahuasca profile Full Neurological Injury profile