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Home/Research/Ayahuasca/Opioid Use Disorder (OUD)

Ayahuasca for Opioid Use Disorder (OUD)

2 papers and 0 clinical trials exploring ayahuasca as a treatment for opioid use disorder (oud).

Compoundclassic psychedelic

Ayahuasca

Ayahuasca is a botanical decoction combining DMT with MAO-inhibiting harmala alkaloids, producing intense psychedelic effects lasting 3-6 hours. Clinical trials show rapid, large antidepressant effects from a single dose, with a favourable safety profile in controlled settings.

Full Ayahuasca profile
IndicationAn estimated 2 million people in the United States have OUD.

Opioid Use Disorder (OUD)

Opioid Use Disorder (OUD) is a prevalent and serious public health issue that is increasingly being targeted for treatment with psychedelics, particularly ibogaine. Recent studies suggest that these compounds may alleviate withdrawal symptoms and reduce cravings, presenting a potential shift in therapeutic approaches to OUD.

Full Opioid Use Disorder (OUD) profile

Academic Research

2 papers
Paywallmeta

Do Hallucinogens Have a Role in the Treatment of Addictions? A Review of the Current Literature

This paper (2021) reviews the current literature regarding LSD, psilocybin, ketamine, ibogaine, and ayahuasca as potential treatments for addiction. The authors conclude that the available evidence is promising, but that more robust research is needed.

Published
March 31, 2021
Journal
SN Comprehensive Clinical Medicine
Authors
Nigam, K. B., Pandurangi, A. K.
Open Accessindividual

A phenomenological analysis of the subjective experience elicited by ibogaine in the context of a drug dependence treatment

This interview study (n=22) analyzed the subjective experiences associated with ibogaine treatment for substance dependence, and found both similarities and differences to effects reported for classic psychedelics.

Published
November 1, 2017
Journal
Journal of Psychedelic Studies
Authors
Schenberg, E. E., de Castro Comis, M. A., Alexandre, J. F. M., Tófoli, L.F., Chaves, B. D. R., da Silveira, D. X.

Clinical Trials

0 trials

No clinical trials have been tagged with both Ayahuasca and Opioid Use Disorder (OUD) yet.

Trials are continuously being added as new studies are registered.

Explore further

Search all Ayahuasca papers Search all Opioid Use Disorder (OUD) trials Full Ayahuasca profile Full Opioid Use Disorder (OUD) profile