DMT for Schizophrenia

2 papers and 0 clinical trials exploring dmt as a treatment for schizophrenia.

CompoundTryptamine

DMT

A powerful, short-acting tryptamine psychedelic found in many botanical sources, known for rapid onset and intense subjective experiences.

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IndicationApproximately 24 million people worldwide are affected by schizophrenia.

Schizophrenia

Schizophrenia is a complex psychiatric disorder characterised by disruptions in thought processes and perception. Recent research into psychedelics has opened new avenues for understanding its neurobiology and exploring potential therapeutic mechanisms, particularly in addressing treatment-resistant symptoms.

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Academic Research

2 papers

Open Accessmeta

Ayahuasca dimethyltryptamine, and psychosis: a systematic review of human studies

This systematic review of case reports found that psychotic episodes following ayahuasca or DMT use are rare but have been documented in both ritual and recreational/non‑controlled settings. Most reported cases involved a personal or family history of psychosis, bipolar/manic disorders or concomitant substance use, supporting psychiatric screening before administration and avoidance of hallucinogens in those with such histories.

Published: February 23, 2017
Journal: Therapeutic Advances in Psychopharmacology
Authors: Bouso, J. C., Dos Santos, R. G., Hallak, J. E.

Paywallindividual

Psychological effects of (S)-ketamine and N,N-dimethyltryptamine (DMT): a double-blind, cross-over study in healthy volunteers

This double-blind study (n=9) of the psychological effects of esketamine and DMT found the positive effects of DMT, and the negative effects of ketamine most resembling those symptoms of schizophrenia.

Published: November 1, 2005
Journal: Pharmacopsychiatry
Authors: Gouzoulis-Mayfrank, E., Heekeren, K., Kovar, K., Neukirch, A., Obradovic, M., Stock, C., Stoll, M.

Clinical Trials

0 trials

No clinical trials have been tagged with both DMT and Schizophrenia yet.

Trials are continuously being added as new studies are registered.

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