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Home/Research/LSD/Fibromyalgia

LSD for Fibromyalgia

2 papers and 0 clinical trials exploring lsd as a treatment for fibromyalgia.

Compoundclassic psychedelic

LSD

LSD is a classic psychedelic ergoline with high potency at microgram doses and an 8-12 hour duration of action, mediated primarily via 5-HT2A receptor agonism. Modern Phase IIb data in generalised anxiety disorder and FDA Breakthrough Therapy Designation for MM120 have reignited clinical development.

Full LSD profile
IndicationApproximately 300 million worldwide are affected by fibromyalgia.

Fibromyalgia

Fibromyalgia is a complex, multifaceted condition affecting individuals through chronic pain and associated symptoms such as depression and anxiety. Emerging research suggests the potential of psychedelics in managing this condition, although robust clinical evidence is still limited.

Full Fibromyalgia profile

Academic Research

2 papers
Open Accessindividual

Potential analgesic effects of psychedelics on select chronic pain conditions: A survey study

A survey of patients with fibromyalgia, arthritis, migraine, tension‑type headache and sciatica found that psychedelic use—especially full doses—was reported to give greater pain relief than conventional medications in all conditions except sciatica; microdoses improved migraine and matched conventional treatment for the other non‑sciatica conditions. These results suggest full and microdoses of classical psychedelics may merit further investigation as treatments for select chronic pain disorders.

Published
August 20, 2023
Journal
European Journal of Pain
Authors
Cavarra, M., Mason, N. L., Kuypers, K. P. C., Bonnelle, V., Smith, W. J., Feilding, A., Kryskow, P., Ramaekers, J. G.
Paywallindividual

Knowledge, Perceptions, and Use of Psychedelics among Individuals with Fibromyalgia

This survey study (n=354) sought to characterize the knowledge, perceptions and past use of psychedelics among people with fibromyalgia (FM). It was found that 29.9% of respondents reported past use of a psychedelic, and perceptions of benefit from use were generally neutral (59.4%) or positive (36.8%). Less than 3% reported that using psychedelics negatively impacted their overall health or pain symptoms. 11 out of 12 patients using psychedelics specifically to treat pain reported improvements in their symptoms.

Published
January 10, 2022
Journal
Journal of Psychoactive Drugs
Authors
Glynos, N. G., Pierce, J., Davis, A. K., Mcafee, J., Boehnke, K. F.

Clinical Trials

0 trials

No clinical trials have been tagged with both LSD and Fibromyalgia yet.

Trials are continuously being added as new studies are registered.

Explore further

Search all LSD papers Search all Fibromyalgia trials Full LSD profile Full Fibromyalgia profile