Pontificia Universidad Catolica de Chile

Pontificia Universidad Catholica de Chile (UC Chile) is one of Chile's most prestigious research universities, whose Division of Anesthesiology in Santiago has conducted ketamine pharmacokinetic/pharmacodynamic research including the Keta-ANI study, which characterized the temporal antinociceptive profile of IV ketamine bolus using the Analgesia Nociception Index and developed an effect-site TCI model for analgesic dosing.