A Retrospective Effectiveness Trial of Ketamine-Assisted Psychotherapy in Adult Patients Coping With Mental Health
Retrospective, single-group effectiveness study (n=1806) assessing Ketamine‑Assisted Psychotherapy (4–6 ketamine sessions plus psychotherapy) for depression, anxiety, and PTSD with follow-up to 6 months.
Details
Retrospective single-group effectiveness trial of KAP delivered across 11 Field Trip Health clinics in North America; intervention comprised 4–6 guided ketamine sessions paired with psychotherapy-only visits after dose 1 and 2 and then after every 2 subsequent doses.
Outcomes were self-reported symptoms of depression, anxiety and post-traumatic stress at 1, 3 and 6 months; analyses used mixed linear models to estimate change from baseline (intention-to-treat), with secondary analyses of case reductions and minimal clinically important differences.