An Open Prospective Trial of IV Ketamine in Suicidal Adolescents

Open, single-group treatment study (n=10) testing safety and effectiveness of a single IV ketamine infusion (0.5 mg/kg over 15 minutes) for adolescents admitted after a suicide attempt; primary outcomes include depressive symptoms and suicidal ideation.

Secondary assessments include decision-making measured by the Iowa Gambling Task. Participants are treated in PACU for infusion and followed by telephone at one and four weeks to assess course and response.