Ayahuasca Assisted Psychotherapy for Grief

Non-randomised, parallel-group trial (n=84) comparing ayahuasca-assisted constructivist therapy, constructivist psychotherapy alone, and no treatment with assessments at baseline, posttest and 3-month follow-up to prevent prolonged or persistent complex bereavement.

Experimental arm receives 9 online psychotherapeutic sessions with one preparation session, two integration sessions and two oral ayahuasca administrations (0.75 mg/kg DMT) after sessions 3 and 6; control arms receive psychotherapy alone or no treatment with option for ayahuasca after follow-up.