Comparing the Effects of Psilocin and Psilocybin in Healthy Adults

This is a randomized, triple-masked, within-subject crossover study in 20 healthy adults comparing physiological and psychological effects of oral psilocin, sublingual psilocin, and oral psilocybin across multiple supervised dosing sessions.

Participants undergo baseline assessments, preparatory visits with trained facilitators, supervised dosing with clinician safety monitoring, and post-session integration; procedures may be repeated up to three additional times per participant.