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Effects of Salvinorin A on Brain Function

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This study evaluates the effects of Salvinorin A (SA). SA is the active ingredient of the plant Salvia divinorum that is known to have been used by Mexican Indians as part of religious rituals. The purpose of this project is to understand what people experience when they consume Salvinorin A.

Details

This fMRI study examines the effects of inhaled salvinorin A on brain activity and connectivity in healthy volunteers (n=13). Participants complete two experimental inhalation sessions: one in a living-room-like setting and one during MRI.

Blinded doses of salvinorin A are administered via inhalation; primary measures include fMRI-derived activity and connectivity, with safety screening, laboratory tests, and monitoring of adverse events.

Topics:Healthy Volunteers

Registry

Registry linkNCT03418714