Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department

Phase I single-group study to evaluate safety and feasibility of a single low-dose IV ketamine (0.2 mg/kg) given to acutely suicidal ED patients; primary outcomes are safety and feasibility metrics.

Participants are observed in the ED for 2 hours post-dose, then transferred for inpatient psychiatric care; depressive and suicidal symptoms are assessed at 0, 2 hours, 24 hours and 72 hours alongside ED staff feasibility surveys.