Investigating the Mechanisms of the Effects of Psilocybin on Visual Perception and Visual Representations in the Brain

This study uses fMRI during a visual perceptual task to characterise how psilocybin alters visual perception and the brain’s representation of visual stimuli in healthy adult participants.

A randomised, double-blind crossover compares different single oral doses of psilocybin (0–14 mg) administered prior to fMRI; outcomes focus on neural mediation of perceptual changes.