Ketamine and Motivational Enhancement Therapy for the Treatment of Tobacco Use Disorder

The purpose of this study is to examine whether ketamine improves treatment outcomes for tobacco use disorder when delivered with brief motivational enhancement therapy. Participants receive IM ketamine once weekly for three weeks paired with a brief motivational enhancement therapy session.

Assessments include questionnaires and saliva samples at each visit; there are two follow-up visits and overall participation lasts approximately eight weeks.