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Ketamine & Crisis Response Plan for Suicidal Ideation in the ED

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This Phase II/III randomized pilot trial (n=24) conducted by The University of Texas Health Science Center at San Antonio aims to assess the feasibility of administering 100mg intramuscular (IM) ketamine alongside a Crisis Response Plan for patients with acute suicidal ideation in the Emergency Department.

Details

Randomised, parallel-group pilot trial comparing a single 100 mg IM ketamine injection plus a one-time CBT-based Crisis Response Plan versus treatment as usual in adults presenting to the ED with acute suicidal ideation.

Primary aims are feasibility and short-term reductions in suicidal ideation; outcomes and safety are assessed at 120 minutes, 3 days and 1 month. Participants are monitored with vital signs and pulse oximetry after dosing and admitted to inpatient psychiatric care for close observation.

Topics:Suicidality

Registry

Registry linkNCT05696691