This observational cohort study (n=500) aims to assess the impact of ketamine injections on analgesia and mood in chronic pain patients with associated mood disorders.
Prospective observational cohort of adult chronic pain clinic patients receiving routine ketamine injections; pre- and post-injection data are collected to evaluate changes in pain and mood.
Outcomes include numeric pain rating scale (≥2-point change considered significant), Likert sleep scale (≥2-point change), GAD-7 for anxiety (≥4-point change) and PHQ-9 for depression (≥5-point change); analyses performed with SPSS using t-tests, ANOVA, chi-square and regression.