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Ketamine Infusion for Symptomatic Improvement in Severe Borderline Personality Disorder: A Pilot Study (BorderKET)

Not yet recruitingRegisteredCTG

Open-label, single-group Phase II pilot (n=38) testing two IV ketamine infusions (0.5 mg/kg each, 40 min, at H0 and H24) plus Good Psychiatric Management in adults with severe BPD; primary outcome at day 9 (BSL-23).

Details

This pilot evaluates change in BPD symptom severity (BSL-23) at day 9 after two intravenous ketamine infusions (0.5 mg/kg over 40 minutes at H0 and H24) delivered alongside Good Psychiatric Management.

Participants are monitored for suicidal ideation, depressive symptoms, healthcare use, and adverse events with follow-up visits through three months; vital signs and AEs are assessed around each infusion.

Topics:Borderline Personality Disorder (BPD)

Registry

Registry linkNCT07099534