Ketamine Infusion Therapy for the Treatment of PTSD in Paramedics

Paramedics with PTSD related to prehospital work receive a series of six one-hour ketamine hydrochloride infusions over three weeks; assessments occur before treatment, after the series, and 30 days post-treatment to assess durability.

Outcome measures include PHQ-9, PCL-5, AUDIT, BAI administered pre/post/30 days, plus RMEQ-30 and a single-item experiential impact survey after the infusion series; study is a prospective cohort (non-probability sample).