Observational prospective cohort (n=7) evaluating change on psychological screening tools before, after, and 30 days following a six-infusion ketamine series in paramedics with work-related PTSD.
Paramedics with PTSD related to prehospital work receive a series of six one-hour ketamine hydrochloride infusions over three weeks; assessments occur before treatment, after the series, and 30 days post-treatment to assess durability.
Outcome measures include PHQ-9, PCL-5, AUDIT, BAI administered pre/post/30 days, plus RMEQ-30 and a single-item experiential impact survey after the infusion series; study is a prospective cohort (non-probability sample).
Six one-hour ketamine infusions administered over three weeks.
Six one-hour IV infusions; dose per site protocol (not specified in registry fragment).