Start
Completion

Ketamine Infusions for PTSD and Treatment-Resistant Depression

CompletedRegisteredCTG

The purpose of this study is to see whether ketamine, when given as repeated infusions, can produce quick and sustained improvement in depression and PTSD symptoms for individuals who have not had their symptoms effectively treated by current treatments.

Details

Pilot, single-group treatment study of six IV ketamine infusions (0.5 mg/kg) administered Monday–Wednesday–Friday over 2 weeks to veterans with treatment-resistant depression and chronic PTSD (n=20).

Participants remain on-site for approximately 3 hours on infusion days; outcomes include depressive and PTSD symptom severity, safety, and durability of response with follow-up visits over 2 months after the infusion period.

Topics:Treatment-Resistant Depression (TRD)

Registry

Registry linkNCT02577250