Ketamine + Mindfulness for Depression

Randomised, double-blind, parallel-group trial in adults with unipolar depression comparing a single intravenous ketamine infusion (0.5 mg/kg over 40 minutes) delivered with either brief mindfulness exercises or matched academic exercises.

Participants receive a 30‑minute preparatory session (mindfulness training or academic tasks) immediately prior to infusion; outcomes assess changes in depression scores following a single infusion.