To learn the long-term impact of depression, bipolar disorder, and suicide risk.
This prospective cohort follow-up (up to 1 year per participant) will re-contact former participants of Protocol 01-M-0254 to assess long-term depressive symptoms, suicide attempts, and ketamine utilisation via online surveys and telephone interviews.
Design comprises two remote phases: Phase 1 online surveys (~30 minutes) assessing current symptoms and treatments; Phase 2 telephone interviews (1–4 hours) for in-depth clinical and treatment history.
Primary endpoint is Beck Depression Inventory score; secondary endpoints include self-reported suicide attempts, self-reported ketamine use, and suicide mortality via National Death Index linkage.
Individuals who previously signed consent for ETPB research as healthy volunteers
Individuals with mood disorders who previously signed consent for ETPB research