Observational prospective cohort collecting outcomes after low-dose IV ketamine infusions for treatment-resistant depression in admitted adult patients.
Prospective descriptive study extracting electronic health record data on adults with treatment-resistant depression who receive physician-ordered ketamine infusions in hospital settings; assessments include QIDS pre and 24 hours post infusion and vital signs monitoring.
Ketamine is administered IV in 50 mL normal saline at either 0.5 mg/kg over 40 minutes or 1 mg/kg over 90 minutes per ICU attending decision; monitoring includes vitals every 15 minutes during infusion and until recovery.
Single-infusion IV ketamine per physician orders for patients with treatment-resistant depression (observational cohort).
Infusion in 50 mL NS; 0.5 mg/kg over 40 minutes or 1 mg/kg over 90 minutes as determined by ICU attending.