Low Dose Ketamine Infusion for the Treatment of Resistant Depression

Prospective descriptive study extracting electronic health record data on adults with treatment-resistant depression who receive physician-ordered ketamine infusions in hospital settings; assessments include QIDS pre and 24 hours post infusion and vital signs monitoring.

Ketamine is administered IV in 50 mL normal saline at either 0.5 mg/kg over 40 minutes or 1 mg/kg over 90 minutes per ICU attending decision; monitoring includes vitals every 15 minutes during infusion and until recovery.