Low-Income Group Psilocybin Assisted Therapy for Depression (LIGPATD)
Open-label, single-group feasibility study (n=20) evaluating group psilocybin-assisted therapy (two psilocybin sessions) for low-income adults with major depression in Oregon.
Details
This feasibility study tests group psilocybin-assisted therapy delivered under Oregon Psilocybin Services to adults with major depression who have incomes at or below 200% of the federal poverty level.
Participants are placed into cohorts of five to six; treatment includes two 90-minute group preparation sessions, two psilocybin dosing sessions guided by two licensed facilitators, and two 90-minute group integration sessions, with a three-month follow-up.
Feasibility outcomes are recruitment, retention, acceptability and safety; other measures include ACE, CEQ, Hamilton Depression Inventory, PROMIS-29, 11-ASC, and structured interviews.