Clinical TrialPersonality & Trait FactorsUnknown status

Personality and Drug Use (PDU)

This observational, naturalistic study (n=1000), conducted by the Psychedelic Data Society (with the Quantified Citizen app), is set to explore the relationship between substance use and personality profiles.

Target Enrollment
1000 participants
Study Type
Phase NA observational
Design
Non-randomized

Detailed Description

This retrospective, case‑control observational study will survey adults worldwide via a mobile app to assess associations between histories of recreational or therapeutic substance use and current personality profiles.

Personality will be measured using the Big Five Inventory‑44 (BFI) and perceived retrospective changes via a self‑constructed Retrospective Personality Scale (RPS); substance use history is self‑reported and participants will be assigned to exposure groups (psychedelics, stimulants, depressants, cannabinoids, mixed, or substance‑naive).

The remote, anonymous design aims to increase accessibility and diversity; personalised result summaries will be shared with participants for transparency and engagement.

Study Arms & Interventions

Psychedelics-only

experimental

Participants reporting past use of classical and non-classical psychedelics.

Interventions

  • Compound

    Self-reported past use of psychedelics (psilocybin, LSD, mescaline, DMT, ayahuasca, 5‑MeO‑DMT, ibogaine, salvia, phenethylamines).

Stimulants-only

experimental

Participants reporting past use of stimulant drugs only.

Interventions

  • Compound

    Self-reported past use of stimulants (cocaine, crack, amphetamines, methamphetamines, prescription stimulants).

Depressants-only

experimental

Participants reporting past use of depressant drugs only.

Interventions

  • Compound

    Self-reported past use of depressants (benzodiazepines, opiates, prescription opioids).

Cannabinoids

experimental

Participants reporting past use of cannabinoid compounds only.

Interventions

  • Compound

    Self-reported past use of cannabinoids (THC, CBD, medical cannabis).

Mixed-use

experimental

Participants reporting past use of both psychedelic and non-psychedelic substances.

Interventions

  • Compound

    Self-reported past use of combinations of psychedelics and non-psychedelic drugs (e.g., MDMA, ketamine, stimulants, opioids, benzodiazepines, cannabis).

Substance-naive

experimental

Participants reporting no past use of listed substances (excluding alcohol and nicotine).

Interventions

  • Compound

    Self-reported absence of past use of study-listed substances (selected 'None of the above').

Participants

Ages
18 – 99
Sexes
Male & Female

Inclusion Criteria

  • 18 years of age or older
  • full legal and mental capacity
  • access to a smartphone with internet to fill in the study measures (available for iOS and Android)

Exclusion Criteria

  • lack of proficiency in English
  • visual impairments (not able to use mobile devices)
  • illiteracy

Study Details

  • Status
    Unknown status
  • Phase
    Phase NA
  • Type
    observational
  • Design
    Non-randomized
  • Target Enrollment1000 participants
  • Timeline
    Start: 2022-11-01
    End: 2023-11-01
  • Topic
    Personality & Trait Factors

Your Library