Psilocybin and Spiritual Practice

Randomised, quadruple-blind, parallel-group study assigning 75 healthy volunteers to one of five groups varying psilocybin dose levels, intensity of support for spiritual practice, and number of psilocybin sessions (2 or 3).

Psilocybin dose is double-blind with ordinal levels from very low to high; participants receive preparation with study guides and follow-up assessments including measures immediately after sessions, 3 weeks after the second psilocybin session, and 4 months after the second session (≈6 months total participation).