Psilocybin as a Treatment for Anorexia Nervosa: A Pilot Study

This pilot interventional study recruits adults with a primary DSM‑5 diagnosis of anorexia nervosa of at least three years’ duration who have not responded to standard treatments; participants receive psilocybin-assisted psychotherapy over three dosing sessions (titrated, maximum single dose 25 mg).

Assessment includes two MRI scans, up to five EEG recordings, psychological measures and interviews across eight study visits, with 12 months of follow-up to evaluate acceptability, efficacy and neural correlates.