Repeated Neurocognitive Measurements in Depressed Patients

This project tracks functioning of multiple neurobiological targets in people with unipolar depression over time, relating fluctuations to real-world functioning and, in a subsample, measuring effects of a single IV ketamine infusion (0.5 mg/kg over 40 minutes).

Design: single-group basic science study with neuroimaging and behavioural assessments; key outcomes include longitudinal neurocognitive measures and acute changes following ketamine in the subsample.